High Definition Endoscopy and Virtual Chromoendoscopy Versus Standard Resolution Endoscopy in Detection of Colon Polyps
- Conditions
- Colonic Adenoma
- Registration Number
- NCT03243669
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Brief Summary
Over the last years a number of new endoscopic imaging modalities have been introduced (high-definition and virtual chromoendoscopy). Given the theoretical advantage of these new imaging techniques, the investigators aimed to investigate their use for the detection of polyps during colonoscopy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2146
- referred for colonoscopy
- signed informed consent
- subtotal colectomy
- known colorectal tumor or polyp prior to colonoscopy
- genetic predisposition to colon cancer namely FAP, HNPCC, Hyperplastic polyposis syndrome, juvenile polyposis, Peutz-Jeghers syndrome
- inflammatory bowel disease
- primary sclerosering cholangitis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Adenoma detection rate (ADR) 7-10 days Percentage of colonoscopies with detection of 1 or more adenomas. ADR is a well-established quality indicator in colonoscopy in the prevalence of adenomas detected (ADR) as recommended by American Society for Gastrointestinal Endoscopy (ASGE)/American College of Gastroenterology Task Force (ACGTF) and European Society of Gastrointestinal Endoscopy (ESGE). Guidelines stipulate to use ADR as main quality indicator in colonoscopy.
- Secondary Outcome Measures
Name Time Method Type of adenomas 7-10 days Subtypes of adenomas: tubular adenomas, tubulovillous adenomas, sessile serrated adenomas and adenocarcinomas
Number of adenomas 7-10 days Adenoma per colonoscopy rate (APCR)
Trial Locations
- Locations (1)
University Hospitals Leuven
🇧🇪Leuven, Belgium
University Hospitals Leuven🇧🇪Leuven, Belgium