跳至主要内容
临床试验/CTRI/2019/05/018899
CTRI/2019/05/018899尚未招募不适用

Functional outcome and pain relief in primary osteoarthritis knee after radio-frequency treatment: a prospective randomised comparison between pulsed radio-frequency of saphenous nerve and adductor canal

Dr Ashok Jadon1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2019年6月5日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Pain Relief

研究概览

简要总结

Knee osteoarthritis (OA) is the most common cause of knee pain and disability. Many non-invasive treatments to treat OA knee pain are available however, they provide only short-term relief. Radio frequency ablation (RFA)of genicular nerves and pulsed radio frequency(PRF) of saphenous nerve (SN) have shown long lasting relief. The adductor canal (AC), which contains saphenous nerve along with other sensory nerves, which supply knee, has been effectively used for postoperative analgesia after total knee arthroplasty (TKA). We have a hypothesis that, PRF of adductor canal (PRF-AC) will provide effective and sustained pain relief in OA knee pain. As there is no comparative study, we wish to conduct a randomised, double blinded comparative study of PRF of saphenous nerve (PRF-SN) and PRF-AC for OA knee pain. Two group of 25 patients in each group will be given either PRF-SN or PRF-AC and will be compared for analgesic efficacy and duration of pain relief. Western Ontario and Mc master Universities Osteoarthritis Index (WOMAC), OXFORD knee score and Visual analogue score (VAS) will be used for assessment of functional outcome along with pain relief. Any complication of procedure, patient satisfaction and change in the medicine use will also be compared. If PRF-AC found to be effective to provide long-term relief, will open a new avenue of management in OA knee pain.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
35.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • Patients suffering with chronic pain of one or both knees due to osteoarthritis of knee for more then3 months and inadequate pain relief with conservative treatment.
  • Radiological evidence of grade II-IV.

排除标准

  • Patients allergic to local anaesthetics.
  • Contraindication to radio frequency treatment.
  • Contraindication to regional anaesthesia.

结局指标

主要结局

Pain Relief

时间窗: 10th day, 1 month, 3 month, 6 month

Improvement in functional scores

时间窗: 10th day, 1 month, 3 month, 6 month

次要结局

  • Requirements of analgesic drugs(Complication of procedure)

研究者

发起方
Dr Ashok Jadon
申办方类型
Other [self]

研究点 (1)

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