Optimization of Hemodynamic Conditions During Caesarean Section Under Spinal Anaesthesia
- Conditions
- Caesarean Section
- Interventions
- Registration Number
- NCT01278238
- Lead Sponsor
- Anestesiavdelingen Baerum Sykehus
- Brief Summary
The purpose of this study is to determine wether intravenous Phenylephrine, administered as start bolus and following continuous infusion (specific dosage per weight), or optimal lower limb bandaging is more effective in preventing hypotension during caesarean section under spinal anaesthesia in healthy women.
The hypothesis is that the Phenylephrine model is superior to lower limb compression in preventing hypotension.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 120
Healthy women Elective caesarean section under spinal anaesthesia Informed consent Age 18-40 ASA 1-2 BMI 18-32 prior to pregnancy Height 160-180 cm
Any form of disease or anomalities:
Heart or vascular disease Cerebrovascular disease Other somatic or psychiatric disease Hypertension or preeclampsia Contraindication against spinal anaesthesia Anomalities concerning pregnancy and foster
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Placebo - Lower limb compression Lower limb compression - Phenylephrine Phenylephrine -
- Primary Outcome Measures
Name Time Method Invasive arterial bloodpressure Until end of operation, up to roughly 1 hour
- Secondary Outcome Measures
Name Time Method pH value from umbilical vessels of the newborn straight after delivery APGAR score of the newborn 1 + 5 + 10 minutes after delivery Need for rescue pressor (ephedrine, phenylephrine) Until end of operation, roughly 1 hour Cardiac Output Until end of operation, roughly 1 hour
Trial Locations
- Locations (1)
Bærum Sykehus
🇳🇴Rud, Akershus, Norway
Bærum Sykehus🇳🇴Rud, Akershus, Norway