Can Shock Indices Be Prognostic Indicators in Sepsis/Septic Shock?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,522
- 试验地点
- 1
- 主要终点
- Age-adjusted Shock Index (aSI)
研究概览
简要总结
We evaluated the ability of shock indices and hemodynamic parameters to predict 28-day ICU mortality.
详细描述
Shock indices and hemodynamic parameters are significant determinants of mortality in adult ICU patients. This study aimed to evaluate the potential of four known shock indices Shock Index (SI), Age-adjusted Shock Index (aSI), Diastolic Shock Index (dSI), and hemodynamic parameters including Heart Rate (HR), Systolic Arterial Blood Pressure (ABPsys), Diastolic Arterial Blood Pressure (ABPdias), and Mean Arterial Blood Pressure (ABPmean) in predicting 28-day ICU mortality in patients diagnosed with sepsis and septic shock.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with a preliminary diagnosis of sepsis/septic shock in the intensive care unit
- •Adult patients aged between 18 and 80 years
排除标准
- •Patients under 18 years old
- •Pregnant patients
- •Patients suspected of having COVID-19 pneumonia
- •Patients with incomplete data
- •Patients for whom outcome information is unavailable due to referral to an external center
- •Patients with confirmed COVID-19, validated by thoracic computed tomography images and nasal swab PCR results
- •Patients discharged from the intensive care unit within 24 hours
结局指标
主要结局
Age-adjusted Shock Index (aSI)
时间窗: During the first 7 hours in the ICU
The predictive power of the Age-adjusted Shock Index (aSI) parameter for 28-day mortality in sepsis patients treated in the intensive care unit.
Diastolic Shock Index (dSI)
时间窗: During the first 7 hours in the ICU
The predictive power of the Diastolic Shock Index (dSI) parameter for 28-day mortality in sepsis patients treated in the intensive care unit.
Shock Index (SI)
时间窗: During the first 7 hours in the ICU
The predictive power of the Shock Index (SI) parameter for 28-day mortality in sepsis patients treated in the intensive care unit.
modified Shock Index (mSI)
时间窗: During the first 7 hours in the ICU
The predictive power of the modified Shock Index (mSI) parameter for 28-day mortality in sepsis patients treated in the intensive care unit.
次要结局
- Systolic Arterial Blood Pressure (ABPsys)(During the first 7 hours in the ICU)
- Mean Arterial Blood Pressure (ABPmean)(During the first 7 hours in the ICU)
- Heart Rate (HR)(During the first 7 hours in the ICU)
- Diastolic Arterial Blood Pressure (ABPdias)(During the first 7 hours in the ICU)
- Age(During the first 7 hours in the ICU)
研究者
Furkan Tontu
Doctor of Anesthesiology and Reanimation
Başakşehir Çam & Sakura City Hospital