OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid elderly: a cluster randomised controlled trial

Completed

• Conditions: polyfarmacie, multimorbiditeit; medication use; Multipel medications

• Registration Number: NL-OMON47041
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Trial is onging in other countries

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-09-16
• Results First Posted: 2020-02-25
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 452

Inclusion Criteria

• People 70 years of age or older
• Multimorbidity: 3 or more coexistent chronic conditions (either defined by 3 distinct ICD-10 codes or based on clinical decision) with an estimated duration of 6 months or more or based on a clinical decision
• Polypharmacy i.e. five or more different regular drugs (defined as authorised medications with registration numbers) for more than 30 days
• If inpatient: Estimated minimal length of stay within the cluster is sufficient to apply the intervention
• If outpatient: Prescribing physician has GP-function and has a planned appointment to conduct intervention

Exclusion Criteria

• Inability to provide informed consent or to obtain informed consent from a proxy for patients with cognitive impairment
• Direct admission to palliative care (planned within < 24 hours after index hospital admission or visit at the ambulatory clinic)
• Has passed or is planned to pass a systematic structured drug review other than the study intervention during the index hospitalisation or stay at the ambulatory clinic or within the last two months

Study & Design

• Study Type: Interventional
• Study Design: Not specified