Aromatherapy Massage for Itching Management in Liver Diseases

Not Applicable

Completed

• Conditions: Skin Moisture; Aromatherapy; Itching; Massage; Liver Diseases; PH Level
• Interventions: Other: aromatherapy massage (sweet almond oil); Other: aromatherapy massage (diluted tea tree oil)

• Registration Number: NCT05367414
• Lead Sponsor: Amine Terzi

Brief Summary

The aim of this study is to determine the effect of aromatherapy massage on itching, comfort, skin pH level and skin moisture in individuals with liver disease.

Research Hypotheses:

H1: Aromatherapy massage has an effect on the level of itching in individuals with itchy liver disease.

H2: Aromatherapy massage has an effect on the general comfort level in individuals with itchy liver disease, H3: Aromatherapy massage has an effect on skin pH level in individuals with itchy liver disease.

H4: Aromatherapy massage has an effect on skin moisture in individuals with itchy liver disease.

Detailed Description

This randomised controlled trial was conducted in order to examine study effect of aromatherapy massage on itching, comfort, skin pH level, and skin moisture among individuals with liver diseases

Study Timeline

• Study Start: 2020-02-13
• Primary Completion: 2021-05-03
• Study Completion: 2021-06-23
• Study First Submitted: 2022-04-18
• Status Verified: 2022-05
• Study First Submitted QC: 2022-05-05
• Study First Posted: 2022-05-10
• Last Update Submitted: 2025-01-27
• Last Update Posted: 2025-01-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• patients who volunteered to participate in the study,
• with a diagnosis of chronic liver disease (liver cirrhosis (primary biliary cirrhosis, alcoholic, cardiac, post-necrotic, cryptogenic cirrhosis, Wilson's Cirrhosis, hemochromatosis), chronic viral hepatitis),
• had no cognitive impairment,
• were not included in the pre-application,
• could answer questions,
• itch score of above 3 (with Visual Analogue Scale).

Exclusion Criteria

• patients are taking antipruritic treatment,
• have itchy skin disease before, ulcer, eczema, etc. in the area to be applied
• patients with dermatological problems, any swelling or signs of inflammation in the area ---to be treated, neuropathy or loss of sensation in the area to be treated
• patients with allergic to tea tree oil, perfume, or cosmetics,
• diagnosed with cancer

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
placebo	aromatherapy massage (sweet almond oil)	Individuals in this group were provided massage with sweet almond oil in addition to routine medical treatment.
aromatherapy	aromatherapy massage (diluted tea tree oil)	In addition to routine medical treatment, massage with diluted tea tree oil was applied to the individuals in this group.

Primary Outcome Measures

Name	Time	Method
Itching	Day 14	Itching was assessed with the 5D Itch Scale. The total score of the scale ranges from 5 to 25, with 5 points indicating the absence of itching and 25 points indicating the highest severity of itching.
skin moisture level	Day 14	DMM brand skin moisture measuring device was used to measure skin moisture level.
skin pH level	Day 14	For pH level measurement, the F-74 G model skin pH measuring device manufactured by HORIBA Scientific and ISFET (Ion Sensitive Field Effect Transistor) 0040-10D model pH electrode produced by HORIBA Scientific were used.
comfort	Day 14	Comfort assessed with the General Comfort Scale. The score to be obtained from the scale varies between 48 and 192. 48 points indicating the low comfort level and 192 points indicating the high comfort level.

Trial Locations

Locations (1)

Artvin Coruh University; 🇹🇷 Artvin, Turkey