Effects of Intake Duration of New Zealand Blackcurrant Extract on Physiological, Cardiovascular and Metabolic Responses at Rest and During Moderate-intensity Exercise in Healthy Males
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Changes in heart rate from baseline with acute intake, one week and two weeks intake of New Zealand blackcurrant extract
研究概览
简要总结
Study will examine the metabolic, physiological and cardiovascular changes by intake of New Zealand blackcurrant extract at rest and during moderate-intensity treadmill walking in healthy males.
详细描述
The investigators will examine effects of acute intake, intermittent intake and chronic intake of New Zealand blackcurrant extract using indirect calorimetry and hemodynamic measurements.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Non-smokers
- •Not taking any supplements
- •No known allergy to berries or berry products
排除标准
- •Sedentary
- •Known high blood pressure
- •On medication
研究组 & 干预措施
new zealand blackcurrant extract
Capsules will be take daily or every other day.
干预措施: New Zealand blackcurrant extract (Dietary Supplement)
control
no capsules will be provided.
干预措施: New Zealand blackcurrant extract (Dietary Supplement)
结局指标
主要结局
Changes in heart rate from baseline with acute intake, one week and two weeks intake of New Zealand blackcurrant extract
时间窗: baseline, acute, one week and two weeks
The investigators will use a beat-to-beat blood pressure monitoring system (Portapres® Model 2, Finapres Medical Systems BV, Amsterdam, The Netherlands). The Portapres® is a beat-to-beat finger pressure analyser that allows the non-invasive continuous measurement of hemodynamic parameters. The finger cuff will be positioned around the same finger of the left hand for each testing. All measurements will be taken in rest and during moderate-intensity exercise. Heart rate will be measured in beats/min.
Changes in total peripheral resistance from baseline with acute intake, one week and two weeks intake of New Zealand blackcurrant extract
时间窗: baseline, acute, one week and two weeks
The investigators will use a beat-to-beat blood pressure monitoring system (Portapres® Model 2, Finapres Medical Systems BV, Amsterdam, The Netherlands). The Portapres® is a beat-to-beat finger pressure analyser that allows the non-invasive continuous measurement of hemodynamic parameters. The finger cuff will be positioned around the same finger of the left hand for each testing. All measurements will be taken in rest and during moderate-intensity exercise. Total peripheral resistance will be measured in (mmHg·min)/L
Changes in stroke volume from baseline with acute intake, one week and two weeks intake of New Zealand blackcurrant extract
时间窗: baseline, acute, one week and two weeks
The investigators will use a beat-to-beat blood pressure monitoring system (Portapres® Model 2, Finapres Medical Systems BV, Amsterdam, The Netherlands). The Portapres® is a beat-to-beat finger pressure analyser that allows the non-invasive continuous measurement of hemodynamic parameters. The finger cuff will be positioned around the same finger of the left hand for each testing. All measurements will be taken in rest and during moderate-intensity exercise. Stroke volume will be measured in mL.
Changes in cardiac output from baseline with acute intake, one week and two weeks intake of New Zealand blackcurrant extract
时间窗: baseline, acute, one week and two weeks
The investigators will use a beat-to-beat blood pressure monitoring system (Portapres® Model 2, Finapres Medical Systems BV, Amsterdam, The Netherlands). The Portapres® is a beat-to-beat finger pressure analyser that allows the non-invasive continuous measurement of hemodynamic parameters. The finger cuff will be positioned around the same finger of the left hand for each testing. All measurements will be taken in rest and during moderate-intensity exercise. Cardiac output will be measured in L/min.
Changes in blood pressure from baseline with acute intake, one week and two weeks intake of New Zealand blackcurrant extract
时间窗: baseline, acute, one week and two weeks
The investigators will use a beat-to-beat blood pressure monitoring system (Portapres® Model 2, Finapres Medical Systems BV, Amsterdam, The Netherlands). The Portapres® is a beat-to-beat finger pressure analyser that allows the non-invasive continuous measurement of hemodynamic parameters. The finger cuff will be positioned around the same finger of the left hand for each testing. All measurements will be taken in rest and during moderate-intensity exercise. Systolic, diastolic and mean arterial blood pressure will be measured in mmHg.
次要结局
- Changes in respiratory exchange ratio from baseline with acute intake, one week and two weeks intake.(baseline, acute, one week and two weeks)
- Changes in oxygen consumption from baseline with acute intake, one week and two weeks intake.(baseline, acute, one week and two weeks)
- Changes in fat oxidation from baseline with acute intake, one week and two weeks intake.(baseline, acute, one week and two weeks)
- Changes in carbon dioxide production from baseline with acute intake, one week and two weeks intake.(baseline, acute, one week and two weeks)
- Changes in carbohydrate oxidation from baseline with acute intake, one week and two weeks intake.(baseline, acute, one week and two weeks)
研究者
Mark Eilisabeth Willems
Professor of Exercise Physiology
University of Chichester