Periodontal Disease and Cardiovascular Disease

Phase 3

• Conditions: Periodontal Diseases
• Interventions: Drug: Triclosan; Drug: Fluoride

• Registration Number: NCT00763165
• Lead Sponsor: Colgate Palmolive

Brief Summary

To access the influence of triclosan dentifrice on the progression of periodontal disease in patients with coronary heart disease.

Detailed Description

Not available

Study Timeline

• Study Start: 2000-11
• Status Verified: 2008-09
• Study First Submitted: 2008-09-26
• Study First Submitted QC: 2008-09-26
• Study First Posted: 2008-09-30
• Last Update Submitted: 2008-09-30
• Last Update Posted: 2008-10-02
• Primary Completion: 2009-12
• Study Completion: 2009-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 438

Inclusion Criteria

• A minimum of 12 uncrowned teeth other than 3rd molars
• Age 18 to 75 years
• Informed consent

Exclusion Criteria

• Prosthetic heart valves
• Prosthetic joint replacement
• Previous infective endocarditis
• Requirement for antibiotic cover for dental treatment
• Current treatment with warfarin

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
A	Triclosan	-
A	Fluoride	-
B	Fluoride	-

Primary Outcome Measures

Name	Time	Method
Periodontal disease	3-5 Years

Trial Locations

Locations (1)

Discipline of Medicine; 🇦🇺 Chermside, Australia