MedPath

Investigating the effect of herbal medicineTrachyspermumammi L on the symptoms of gastro-oesophageal reflux

Phase 3
Recruiting
Conditions
Patients with gastroesophageal reflux.
Gastro-esophageal reflux disease
Registration Number
IRCT20220619055216N1
Lead Sponsor
Yasouj University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
120
Inclusion Criteria

Being 18-60 years old
Consent to participate in the study and sign the informed consent form
Diagnosing gastroesophageal reflux by gastroenterologist based on ROME lll criteria
Body mass index (BMI) less than 30 (BMI>30)
Absence of systemic diseases
Absence of neurological defects

Exclusion Criteria

Taking antibiotics or non-steroidal anti-inflammatory drugs 2 weeks before the study
Previous participation in studies similar to the current research
Drug or alcohol abuse
Existence of gastrointestinal malignancy based on history, physical examination, laboratory tests (for example, the number of white blood cells, CRP, ESR, and upper endoscopy)
Liver and kidney function disorders based on laboratory tests
Pregnancy
History of severe allergy to medicinal plants
History of upper gastrointestinal surgery and serious diseases such as heart failure, diabetes, epilepsy, previous or current significant psychiatric disorders

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Reflux Symptom Index. Timepoint: Before and after the intervention. Method of measurement: reflux symptom index questionnaire.;Health-related quality of life - gastroesophageal reflux disease (GERD-HRQL. Timepoint: Before and after the intervention. Method of measurement: Health-related quality of life - gastroesophageal reflux disease (GERD-HRQL).
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath