Clinical Trial for Preoperative High Intensity Interval Training (HIT) Prior to Oncological Esophagectomy

Not Applicable

Recruiting

• Conditions: C15.1; Thoracic part of oesophagus

• Registration Number: DRKS00024938
• Lead Sponsor: niversitätsklinikum Mannheim

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-09-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Age between 18 and 80 years
- male and female participants with histological diagnosis of andeocarcinoma or squamous cell carcinoma of the esophagus
- non-palliative surgical therapy of esophageal cancer at University Hospital Mannheim
- Written consent of the participant
- four-week time span free of radiotherapy or chemotherapy ahead of surgical therapy
- physical ability for ergometric testing on a bicycle

Exclusion Criteria

- Patients with severe cardiac or pulmonary disease
- physical inability for ergometry test on a bicycle
- missing ability for consent
- language barrier
- predictable non-compliance
- non-resectable esophageal cancer
- pregnancy
- time-span short of four weeks prior to surgical therapy and after ending of radiotherapy or chemotherapy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
feasibility of a four-week training program prior to surgical therapy

Secondary Outcome Measures

Name	Time	Method
As a secondary endpoint we will investigate, if there is a change in musclemass, nutritional status via lab results, postoperative pain, postoperative complications as well as mean hospital stay when comparing patients receiving preoperative physical training and patients not receiving physical training. Furthermore, we would like to document laboratory parameters, perceived physical fitness, measured physical fitness, BMI and inflammatory markers prior to training, prior to surgery and after surgery.