跳至主要内容
临床试验/CTRI/2024/05/067278
CTRI/2024/05/067278尚未招募不适用

Comparative evaluation of segmental spinal anaesthesia with conventional spinal anaesthesia in endoscopic transurethral surgery

Pt BD Sharma University of health sciencesPGIMS Rohtak Haryana1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2024年5月24日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
1.Upper level of sensory blockade

研究概览

简要总结

There are a number of advantages of thoracic segmental spinal anaesthesia firstly, there is no sympathetic blockade of lower limbs causing significantly lesser venodilation in the lower extremities and therefore there is lesser decrease in the preload to heart which provides better hemodynamic stability. Secondly, nerve roots in the thoracic segments of spinal cord are thinner,as well as the amount of CSF at thoracic levels is comparatively less, which favours efficient blockade with lower doses of anaesthetic drugs. Thirdly, the patients have motor control over their legs during the surgery and patients exhibit a better level of satisfaction and decreased anxiety during the procedure.Various studies have concluded that segmental spinal anaesthesia is a safe and effective method for many surgeries like laparoscopic cholecystectomies, breast cancer lumpectomies, and abdominal cancer surgeries. However, this technique in endoscopic transurethral surgeries remains unacknowledged.

Encouraged by the results of above studies, we plan to study the efficacy of using segmental spinal anaesthesia as the sole regional anaesthetic technique for endoscopic transurethral surgery. We hypothesized that segmental spinal anaesthesia could be a potential alternative to spinal anaesthesia for patients undergoing transurethral surgery.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Patients in the age group 18 to 70 years of either gender, belonging to American society of anaesthesiologist (ASA) physical status 1and 2 scheduled for endoscopic urology study will be included will recieve 1ml of 0.5% isobaric ropivacaine and 20 ug fentanyl in segmental spinal anaesthesia.

排除标准

  • Patients in the age group 18 to 70 years of either gender, belonging to American society of anaesthesiologist (ASA) physical status 1and 2 scheduled for endoscopic urology study will be included will receive spinal anaesthesia with 2ml of 0.5% hyperbaric ropivacaine and 20 ug fentanyl.

结局指标

主要结局

1.Upper level of sensory blockade

时间窗: 1.1minutes,2minutes,3minutes,4 minutes,5minutes,10 minutes,15minutes,30minutes,45minutes | 2.Motor blockade at 10 minutes of subarachnoid block and at the end of surgery | 3.Hemodynamic parameters at baseline,1minutes,2 minutes,3minutes,4minuted,5minutes,10 minutes,15 minutes,30 minutes,45 minutes,55 minutes, 55 minutes,upto 15 minutes after surgery

2.Motor blockade

时间窗: 1.1minutes,2minutes,3minutes,4 minutes,5minutes,10 minutes,15minutes,30minutes,45minutes | 2.Motor blockade at 10 minutes of subarachnoid block and at the end of surgery | 3.Hemodynamic parameters at baseline,1minutes,2 minutes,3minutes,4minuted,5minutes,10 minutes,15 minutes,30 minutes,45 minutes,55 minutes, 55 minutes,upto 15 minutes after surgery

3.Hemodynamic parameters

时间窗: 1.1minutes,2minutes,3minutes,4 minutes,5minutes,10 minutes,15minutes,30minutes,45minutes | 2.Motor blockade at 10 minutes of subarachnoid block and at the end of surgery | 3.Hemodynamic parameters at baseline,1minutes,2 minutes,3minutes,4minuted,5minutes,10 minutes,15 minutes,30 minutes,45 minutes,55 minutes, 55 minutes,upto 15 minutes after surgery

次要结局

  • Time of first rescue analgesia(Patient’s and surgeon’s satisfaction scores)

研究者

发起方
Pt BD Sharma University of health sciencesPGIMS Rohtak Haryana
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Prashant Kumar

Pt BD Sharma Postgraduate Institute of Medical Sciences

研究点 (1)

Loading locations...

相似试验