NCT03276481已完成不适用
Prospective Evaluation of Gustatory Function (Taste) In Patients Undergoing Autologous Hematopoietic Cell Transplantation for Multiple Myeloma
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 47
- 试验地点
- 1
- 主要终点
- Feasibility of comprehensive chemical gustometry in participants with multiple myeloma undergoing autologous HCT
研究概览
简要总结
The purpose of this study is to study taste disturbances on patients with myeloma who received high dose melphalan.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 21 or above with diagnosis of multiple myeloma (myeloma is almost unheard of in patients less than 21 years of age).
- •Scheduled to receive conditioning chemotherapy with melphalan followed by upfront or salvage autologous peripheral blood hematopoietic stem cell transplantation
- •English or Spanish speaking
- •Calculated creatinine clearance > 40 mL/min
排除标准
- •Prior head and neck radiation.
- •Severe periodontal infection. Poor oral hygiene and dentition as determined by pre HCT dental assessment.
- •Pregnancy
- •Patients with pre-existing moderate-severe dysgeusia
结局指标
主要结局
Feasibility of comprehensive chemical gustometry in participants with multiple myeloma undergoing autologous HCT
时间窗: Change from baseline assessment up to 100 days
The primary objective of this protocol is to evaluate the feasibility of comprehensive chemical gustometry in participants with MM undergoing autologous HCT. Chemical gustometry will be evaluated at baseline and on days -1, 7, 14, 30 and 100.
次要结局
未报告次要终点
研究者
研究点 (1)
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