The Utility and Validity of Dynamic Chest Radiography in Cystic Fibrosis

iverpool Heart and Chest Hospital0 个研究点目标入组 154 人开始时间: 2019年12月5日最近更新: 2023年5月22日

适应症

试验速览

2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/32217535 protocol (added 30/03/2020) 2022 Results article in https://doi.org/10.1148/radiol.212641 (added 15/03/2022) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37147023/ Feasibility results (added 09/05/2023)

•1. Potentially pregnant or lactating
•2. Refusal or inability to provide informed consent
•3. Unable or unwilling to sit or stand to perform DCR in the radiology department
•4. Unable or unwilling to follow tidal breathing instructions (e.g., holding breath or taking a deep breath)
•5. Unable to perform reproducible spirometry and/or full pulmonary function studies within ATS-ERS criteria
•6. Any serious or active medical or psychiatric illness, which in the opinion of the investigators, would interfere with subject treatment, assessment, or compliance with the protocol
•7. For those in the validation part of the study: suffering an acute exacerbation of underlying CF
•8. For those in the validation part of the study: known to be MRSA positive
•9. For those in the validation or exacerbation parts of the study: significant radiation exposure within the last year (for example, numerous CT scans of chest)
•10. Involved, either currently or recently, in other studies involving non-routine exposure to sources of ionising radiation

发起方

iverpool Heart and Chest Hospital