Randomized Controlled Trial of Psychodynamic Psychotherapy vs. Applied Relaxation for Panic Disorder
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 49
- 试验地点
- 2
- 主要终点
- PDSS (panic disorder severity scale)
研究概览
简要总结
This study will determine the effectiveness of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training in treating adults with panic disorder.
详细描述
This is a randomized controlled trial of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training, a less active form of treatment in other studies, for adults with primary Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) panic disorder.
Forty nine patients who have signed written consent who have primary DSM-IV panic disorder have been entered into the study. Randomization has been stratified by presence of major depression and use of psychoactive, anti-panic medications. Medications, if present, have been held constant. All patients have received 24 sessions of either psychodynamic psychotherapy, or applied relaxation training for panic disorder. This study is currently closed for recruitment, although final follow-up assessments have yet to be completed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 55 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-55 years old
- •Primary DSM-IV panic disorder with or without agoraphobia
- •Severity 5/8 minimum on the Anxiety Disorders Interview Schedule
排除标准
- •Psychosis
- •Unstable medication dosage
- •Unwilling to discontinue ongoing psychotherapy
- •Organic mental syndrome
- •Substance use or abuse
结局指标
主要结局
PDSS (panic disorder severity scale)
时间窗: termination, 2, 4, 6, 12 month f/u
次要结局
- SDS (Sheehan disability scale)(termination, 2, 4, 6, 12 month f/u)
- HARS (Hamilton anxiety rating scale)(termination, 2, 4, 6, 12 month f/u)
- HDRS (Hamilton depression rating scale)(termination, 2, 4, 6, 12 month f/u)
