Fluid responsiveness between early goal directed fluid therapy and ultrasonography guided fluid resuscitation in septic shock patients : A randomized control trial study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- i)Mean arterial pressure, central venous pressure, heart rate, respiratory rate, urine output will be assessed.
研究概览
简要总结
a) To compare early goal directed fluid therapy with ultrasonography guided fluid responsiveness in septic shock patients admitted in Intensive Care Unit.
b) To compare hemodynamic variables in two groups during the study period
c) To find out the proportion of patients developing fluid overload during study period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •i) patients age more than 18 years and less than 65 years with a definitive diagnosis of septic shock.
- •ii) patients fulfilling two or more systemic inflammatory response syndrome criteria.
排除标准
- •i) pre-existing valvular or structural heart disease patients.
- •ii) known history of acute coronary syndrome, acute pulmonary edema.
- •iii) patients age less than 18 years and pregnant females iv) patient under invasive mechanical ventilator.
结局指标
主要结局
i)Mean arterial pressure, central venous pressure, heart rate, respiratory rate, urine output will be assessed.
时间窗: i)Mean arterial pressure, central venous pressure, heart rate, respiratory rate, urine output will be assessed every 30 minutes upto 6 hours of admission. | ii) Inferior vena cava diameter and collapsibility will be assessed every 30 minutes upto 6 hours of admission.
ii) Inferior vena cava diameter and collapsibility will be assessed.
时间窗: i)Mean arterial pressure, central venous pressure, heart rate, respiratory rate, urine output will be assessed every 30 minutes upto 6 hours of admission. | ii) Inferior vena cava diameter and collapsibility will be assessed every 30 minutes upto 6 hours of admission.
次要结局
- 1) To compare any signs and symptoms of fluid overload during study period(First 6 hours since admission)
研究者
Sathi Dhar
Agartala Government Medical College.