Biomarkers of Early Chronic Obstructive Pulmonary Disease (COPD) in Smokers - Longitudinal Study

Completed

• Conditions: Chronic Obstructive Pulmonary Disease; Cardiovascular Disease; Lung Cancer

• Registration Number: NCT02076061
• Lead Sponsor: Lund University

Brief Summary

This is a longitudinal observational study to identify and validate protein biomarkers for COPD (chronic obstructive pulmonary diseases) and cardiovascular disease in smokers and ex-smokers attending primary care. Special emphasize is to correlate biomarkers to different phases of COPD, to progression of the disease, and to treatment of the disease. Furthermore, linkage between COPD, cardiovascular disease, and lung cancer will be investigated by identifying protein biomarkers.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-02
• Study First Submitted: 2014-02-27
• Study First Submitted QC: 2014-02-27
• Study First Posted: 2014-03-03
• Primary Completion: 2020-04-30
• Study Completion: 2020-04-30
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-23
• Last Update Posted: 2022-08-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

Diagnosed with COPD Gold stage 0-IV

Exclusion Criteria

Patients with inflammatory diseases Patients with cancer Patients using immune system regulating drugs

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Advanced disease etiology requiring hospitalization.	2 years

Trial Locations

Locations (1)

Örestadskliniken; 🇸🇪 Malmö, Sweden