BILATERAL COMPARISON OF LIQUID PARAFFIN AND CREAM BASE ON TRANSEPIDERMAL WATER LOSS AMONG PSORIASIS PATIENTS: A RANDOMIZED TRIA
- Conditions
- Psoriasis is a common chronic inflammatory disease. Psoriasis patients experience pain,discomfort and skin dryness. Skin moisturizing is a major component of treatment for these patients.RANDOMIZED CONTROL TRIAL / PSORIASIS / TRANSEPIDERMAL WATER LOSS / SKIN HYDRATION
- Registration Number
- TCTR20160404002
- Lead Sponsor
- Institute of Dermatology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 100
The eligible participants were patients who were diagnosed with plaque psoriasis and had mild severity of psoriasis with PASI score less than 10 and had the following characteristics:
3.2.1.1Were male or female.
3.2.1.2Aged of 18 years or above.
3.2.1.3Willing to be in the study and gave written informed consent.
The participants who had the following characteristics were excluded from the study:
3.2.2.1 In condition that could not take care of themselves.
3.2.2.2 Had chronic diseases such as liver or kidney diseases.
3.2.2.3 Had history of allergy to liquid paraffin or cream base.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Transepidermal water loss (TEWL) at 4-week baseline, at 60 minutes after applying the agents and at the 4th week study was conducted among 100 participants with mild plaque type psoriasis [Psoriasis Area and Sever
- Secondary Outcome Measures
Name Time Method Skin hydration, PASI Score, EQ-5D-5L baseline, at 60 minutes after applying the agents and at the 4th week study was conducted among 100 participants with mild plaque type psoriasis [Psoriasis Area and Sever