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BILATERAL COMPARISON OF LIQUID PARAFFIN AND CREAM BASE ON TRANSEPIDERMAL WATER LOSS AMONG PSORIASIS PATIENTS: A RANDOMIZED TRIA

Not Applicable
Completed
Conditions
Psoriasis is a common chronic inflammatory disease. Psoriasis patients experience pain&#44
discomfort and skin dryness. Skin moisturizing is a major component of treatment for these patients.
RANDOMIZED CONTROL TRIAL / PSORIASIS / TRANSEPIDERMAL WATER LOSS / SKIN HYDRATION
Registration Number
TCTR20160404002
Lead Sponsor
Institute of Dermatology
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
100
Inclusion Criteria

The eligible participants were patients who were diagnosed with plaque psoriasis and had mild severity of psoriasis with PASI score less than 10 and had the following characteristics:
3.2.1.1Were male or female.
3.2.1.2Aged of 18 years or above.
3.2.1.3Willing to be in the study and gave written informed consent.

Exclusion Criteria

The participants who had the following characteristics were excluded from the study:
3.2.2.1 In condition that could not take care of themselves.
3.2.2.2 Had chronic diseases such as liver or kidney diseases.
3.2.2.3 Had history of allergy to liquid paraffin or cream base.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Transepidermal water loss (TEWL) at 4-week baseline, at 60 minutes after applying the agents and at the 4th week study was conducted among 100 participants with mild plaque type psoriasis [Psoriasis Area and Sever
Secondary Outcome Measures
NameTimeMethod
Skin hydration, PASI Score, EQ-5D-5L baseline, at 60 minutes after applying the agents and at the 4th week study was conducted among 100 participants with mild plaque type psoriasis [Psoriasis Area and Sever
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