Retrospective Matched Pair Analyses for Evaluating the Influence of Hemodynamically Focussed Transesophageal Echocardiography (hTEE) on Postoperative Outcome in Cardiosurgery Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Cumulative dosage of catecholamine application
研究概览
简要总结
Compromised tissue oxygenation during surgery may negatively influence patient outcome. Primary cause of insufficient tissue oxygenation is reduced cardiac output due to hypovolemia and/or reduced cardiac contractility. In cardiac surgery patients especially, postoperative pericardia effusion and/or tamponade may further compromise cardiac function. Today, hemodynamically instable patients are often monitored by means of pulmonal artery catheters or transpulmonary thermodilution. However, these methods only allow quantification of functional limitations. Underlying causes may be investigated by relatively recent technology through hemodynamically focussed transesophageal echocardiography (ClariTEE(R) ImaCor) that also provide the possibility of continuous monitoring. It has been reported that a training program consisting of six hours may enable physicians who are unexperienced in the field of echocardiography to apply this new method. Up to now, there is no evidence whether this methods is associated with improved postoperative outcome.
Therefore we hypothesize that continuous hemodynamically focussed transesophageal echocardiography positively influences patient outcome (primary hypothesis). Furthermore, its application may decrease hospital expenses (secondary hypothesis).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •elective, cardiac surgery
- •hemodynamic instability or placement of hTEE/PICCO (Pulse Contour Continuous Cardiac Output) /PAC (Pulmonary Arterial Catheter) within 12 hours of ICU admission
排除标准
- •pregnant/breastfeeding women
结局指标
主要结局
Cumulative dosage of catecholamine application
时间窗: three days beginning upon placement of device
次要结局
- duration of postoperative ventilation(first postoperative day until extubation (2 days on average))
- incidence of renal failure(three days beginning upon placement of device (or icu admission in control patients, respectively))
- incidence of hemodialysis(three days beginning upon placement of device (or icu admission in control patients, respectively))
- length of hospital stay(participants will be followed for the duration of hospital stay, an expected average of 3 weeks)
- in-hospital mortality(participants will be followed for the duration of hospital stay, an expected average of 3 weeks)
- cost of hospital stay(participants will be followed for the duration of hospital stay, an expected average of 3 weeks)
- degree and duration of other vasoactive substances(degree and duration of other vasoactive substances three days beginning upon placement of device (or icu admission in control patients, respectively))
- fluid balance(day 1, 2 and 3, beginning upon placement of device (or icu admission in control patients, respectively))
- degree and duration of lactate acidosis(degree and duration of other vasoactive substances three days beginning upon placement of device (or icu admission in control patients, respectively))
研究者
Michael Sander
Univ.-Prof. Dr. med.
Charite University, Berlin, Germany
