Different Chemotherapy Protocols Combined With Intensity Modulated Radiation Therapy in Patients With Locally Advanced Nasopharyngeal Carcinoma

Not Applicable

Completed

• Conditions: Drug-Related Side Effects and Adverse Reactions
• Interventions: Drug: Docetaxel; Drug: Cisplatin

• Registration Number: NCT03177174
• Lead Sponsor: Luo yanrong

Brief Summary

This study was to evaluate the efficacy ,toxic reaction and safety of different chemotherapy combined with radiotherapy on patients with locally advanced nasopharyngeal carcinoma.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-03-18
• Study First Submitted QC: 2017-06-05
• Study First Posted: 2017-06-06
• Study Start: 2017-06-12
• Primary Completion: 2020-01-01
• Status Verified: 2020-02
• Study Completion: 2020-02-01
• Last Update Submitted: 2020-02-06
• Last Update Posted: 2020-02-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Patients > 18, <70 years old, with locally advanced nasopharyngeal carcinoma.

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Exclusion Criteria

• patients who had accepted radiotherapy before patients with any ather types of cancer

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Docetaxel	Docetaxel	-
DocetaxelCisplatin	Cisplatin	Cisplatin combined with Docetaxel
Cisplatin	Cisplatin	-
DocetaxelCisplatin	Docetaxel	Cisplatin combined with Docetaxel

Primary Outcome Measures

Name	Time	Method
changes in toxic reaction	5 years	incidence rate of the toxic reaction between three groups

Secondary Outcome Measures

Name	Time	Method
over survival	5 years	differences of over survival rate between three groups

Trial Locations

Locations (1)

Chinese PLA general hospital; 🇨🇳 Beijing, China