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Clinical evaluation on activation of coagulation and fibrinolytic system during major cardiovascular surgery

Not Applicable
Conditions
major cardiovascular surgery with use of cardiopulmonary bypass
Registration Number
JPRN-UMIN000010866
Lead Sponsor
Teikyo University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

patients with congenital bleeding diathesis, patients with thrombocytopenia less than 100,000/uL continuing more than one month, patients with taking oral anticoagulant/antiplatelet agents

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
activated factor VII, thrombin-antithrombin complex (TAT), fibrin monomer, fibrin degradation product (FDP), D-dimer, plasmin-plasmin inhibitor complex (PIC), fibrinogen, PT, APTT, platelet count, hemoglobin, from just before the start of cardiopulmonary bypass until entrance into the intensive care unit
Secondary Outcome Measures
NameTimeMethod
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