Cell Culture of Glioma Specimens for in Vitro Preclinical Studies
- Conditions
- Brain Tumor
- Registration Number
- NCT01125826
- Lead Sponsor
- Albany Medical College
- Brief Summary
The purpose of this study is to culture primary human brain tumor cells with the specific aims of:
1. Develop primary cultures from human brain tumor surgical specimens
2. Determine the genetic and molecular fingerprints of brain tumors that may have prognostic significance
3. Delineate the mechanisms underlying oncogenesis of brain tumors.
4. Perform in vitro assays with brain tumor derived primary cultures to assess the efficacy of novel therapeutic agents.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- Patients 18 years of age or older undergoing surgical resection for glioma
Exclusion Criteria
- Under 18 years of age
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms drive oncogenesis in primary glioma cultures from NCT01125826?
How do genetic fingerprints from NCT0125826 glioma cultures inform patient selection biomarkers?
What in vitro drug efficacy data from NCT01125826 supports novel therapeutic targets for gliomas?
Are there comparative studies of glioma cell culture models versus standard-of-care treatment outcomes?
What adverse events are associated with glioma cell culture-derived therapies and how are they managed?
Trial Locations
- Locations (1)
Albany Medical Center
🇺🇸Albany, New York, United States
Albany Medical Center🇺🇸Albany, New York, United StatesTyler Kenning, MDContactkennint@mail.amc.edu