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临床试验/NCT01823094
NCT01823094已完成不适用

CTP (Computed Tomography Perfusion) Imaging of Lung Cancer

University of California, Davis1 个研究点 分布在 1 个国家目标入组 14 人开始时间: 2013年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
14
试验地点
1
主要终点
Yield of conducting CTP studies

研究概览

简要总结

Investigators hope to learn more about how to use computed tomography (CT) scans to measure blood flow in lung tumors and how it may change in response to treatment. This measurement technique is called computed tomography perfusion (CTP). CT scanners use X-rays to produce 3-dimensional images of the body.

Currently, doctors determine the response to treatment by measuring the size of the tumor. Investigators are trying to find out if measuring the blood flow in the tumor is equal to or better than measuring the size of the tumor.

详细描述

This is an experimental study of CT perfusion (CTP) imaging in subjects with non-small cell lung cancer. The objectives of this study are to demonstrate the feasibility of CT blood flow measurements in lung cancer, to develop a foundation for the use of CT blood flow measurements in lung cancer to assess the response to treatment, and to develop an optimized CTP imaging protocol for evaluating blood flow in solid body tumors. In this study, tumor blood flow will be evaluated at baseline and follow-up routine CT examinations of patients with non-small cell lung cancer, and the response of tumor blood flow will be recorded as a secondary endpoint. This research study will entail two study visits - one required and one optional - which will coincide with regularly scheduled standard of care CT scans.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • adult patients with non small cell lung cancer who receive, or are considered for, systemic therapy

排除标准

  • renal failure pregnancy known contrast allergy

结局指标

主要结局

Yield of conducting CTP studies

时间窗: 2 years

Yield is determined as the percentage of assessable CTP studies, relative to all performed studies

次要结局

  • Variability of CTP measurements(2 years)
  • Magnitude of treatment induced changes in tumor blood flow(2 years)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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