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Clinical Trials/NCT05022121
NCT05022121
Completed
Not Applicable

Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain

University of Minnesota2 sites in 1 country42 target enrollmentJanuary 26, 2022

Overview

Phase
Not Applicable
Intervention
Supported Biopsychosocial Self-Management (SBSM)
Conditions
Low Back Pain
Sponsor
University of Minnesota
Enrollment
42
Locations
2
Primary Endpoint
Percentage of Screened Participants Who Are Female
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Guidelines advocate several complementary modalities as alternatives to drugs and other invasive treatments for chronic low back pain (LBP) conditions. However, there is little high-quality research investigating treatments for back-related leg pain, one of the more severe and disabling presentations of LBP. The investigators are conducting a pilot study to assess the feasibility of a future phase II multi-site randomized clinical trial (RCT). The future trial will assess the comparative effectiveness of a novel supported biopsychosocial self-management (SBSM) intervention versus Medical Care (MC).

Registry
clinicaltrials.gov
Start Date
January 26, 2022
End Date
February 20, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Back-related leg pain (BRLP) consistent with the Quebec Task Force (QTF) classifications 2-4 (radiating pain into proximal or distal extremity with or without neurological signs).
  • 18 years of age or older.
  • Back-related leg pain severity of 3 or higher at all screening assessments (0 to 10 scale)
  • Episode duration of 12 weeks or more
  • Ability to read English fluently

Exclusion Criteria

  • Spinal stenosis (QTF 7)
  • Specific, non-mechanical causes of BRLP (QTF 11; e.g. infection, tumor)
  • Contraindications to study interventions (e.g. spinal fracture (QTF 5))
  • Inflammatory conditions of the lumbar spine (QTF 11)
  • Lumbar fusion
  • Progressive neurological deficits
  • Cauda equina syndrome
  • Pregnancy, nursing
  • Ongoing care from another healthcare provider for BRLP
  • Severe unmanaged comorbid conditions (e.g. substance abuse, major depressive disorder, stage 3 hypertension).

Arms & Interventions

Supported Biopsychosocial Self-Management (SBSM)

Supported Biopsychosocial Self-Management (SBSM)

Intervention: Supported Biopsychosocial Self-Management (SBSM)

Medical Care

Medical Care

Intervention: Medical Care

Outcomes

Primary Outcomes

Percentage of Screened Participants Who Are Female

Time Frame: 6 month period of active study screening

As a measure of recruitment feasibility, the number of female participants in the study is reported

Percentage of Enrollees in Medical Care Group Reporting Taking Medications as Prescribed

Time Frame: Through study treatment, an average of 3 months

As a measure of participant treatment adherence associated with feasibility, the number of enrollees who are part of the medical care arm self-reporting taking medications as prescribed is reported.

Percentage of Provider Visits Where All Required Intervention Activities Were Delivered

Time Frame: Through study treatment, an average of 3 months

As a measure of provider fidelity, the percentage of provider vists where 100% of required intervention activities were delivered is reported.

Percentage of Enrollees Attending Required Sessions

Time Frame: Through study treatment, an average of 3 months

As a measure of participant treatment adherence associated with feasibility, the number of enrollees attending the minimum number of required study sessions (6 for SBSM and 2 for Medical Care) are reported.

Percentage of Enrollees in Supported Biopsychosocial Self-management Group Reporting Participation in Home Practice

Time Frame: Through study treatment, an average of 3 months

As a measure of participant treatment adherence associated with feasibility, the number of enrollees who are part of the supported biopsychosocial self-management arm of the study who self-report participation in home treatment practice is reported.

Percentage of Enrollees Completing the Month 6 Assessment

Time Frame: Month 6 assessment

As a measure of data collection feasibility, the number of enrollees completing the month 6 assessment is reported.

Percentage of Enrollees Not Receiving Any Treatment

Time Frame: Through study treatment, an average of 3 months

As a measure of intervention acceptability and credibility associated with feasibility, the number of enrollees not receiving any treatment is reported.

Percentage of Enrollees Completing the Month 3 Assessment

Time Frame: Month 3 assessment

As a measure of data collection feasibility, the number of enrollees completing the month 3 assessment is reported.

Percentage of Weekly Pain Severity and Frequency Assessments Completed

Time Frame: Through completion of all weekly assessments, an average of 6 months

As a measure of data collection feasibility, the number of weekly pain severity and frequency assessments completed by participants is reported.

Percentage of Enrolled Participants Who Are From Racial or Ethnic Minority Populations

Time Frame: 6 month period of active enrollment

As a measure of enrollment feasibility, the number of participants enrolled from racial or ethnic minority populations is reported.

Percentage of Enrollees Receiving Prohibited Treatments

Time Frame: Through study treatment, an average of 3 months

As a measure of intervention acceptability and credibility associated with feasibility, the number of enrollees receiving prohibited treatments, (contamination), during the 12-week intervention phase of the study is reported.

Number of Particpants Screened Per Month

Time Frame: 6 month period of active study screening

As a measure of recruitment feasibility, the average number of participants screened per month is reported

Percentage of Screened Participants Who Are From Racial or Ethnic Minority Populations

Time Frame: 6 month period of active study screening

As a measure of recruitment feasibility, the number of participants from racial or ethnic minority populations is reported.

Number of Participants Enrolled Per Month

Time Frame: 6 month period of active study screening

As a measure of enrollment feasibility, the average number of participants recruited per month is reported.

Percentage of Enrolled Participants Who Are Female

Time Frame: 6 month period of active study enrollment

As a measure of enrollment feasibility, the number of female participants enrolled in the study is reported.

Percentage of Enrollees Satisfied With Treatment

Time Frame: Through study treatment, an average of 3 months

As a measure of intervention acceptability and credibility associated with feasibility, treatment satisfaction was reported by participants via a 7-point Likert satisfaction scale, ranging from 1, "completely satisfied," to 7, "completely dissatisfied," where lower numbers indicate greater satisfaction. The percentage of enrollees satisfied with treatment is reported as a percent value representing those who choose "somewhat satisfied" or better on the scale.

Study Sites (2)

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