The effects of a multi-modal exercise program on cognition and physical functioning in older women: a randomised controlled trial.

Not Applicable

• Conditions: Age related cognitive decline; Age related physical decline; Public Health - Health promotion/education; Neurological - Studies of the normal brain and nervous system; Musculoskeletal - Normal musculoskeletal and cartilage development and function

• Registration Number: ACTRN12612000451808
• Lead Sponsor: Sue Vaughan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-04-23
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

Potential participants will be included in the study if they are:
Female
Aged 65-75 years
Have normal cognitive function as assessed by the telephone interview of cognitive status (TICS).

Exclusion Criteria

People are excluded from the study if they score below 21 on the Telephone Interview of Cognitive Status (TICS); or if they are unable to obtain written clearance from a General Practitioner for serious health problems such as unstable heart or metabolic conditions. Individuals are also ineligible where there is a diagnosis of dementia or Parkinson’s disease or there is a report of a recent head injury.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive test performance related to executive functions: working memory (Letter-Number Sequencing Test), inhibition (Stroop test), shifting (Trailmaking Test Parts A & B), simple and complex reaction time (1 choice and 5 choice - computer based assessment), verbal fluency (Controlled Oral Word Association Test).[Baseline and 16 weeks]

Secondary Outcome Measures

Name	Time	Method
Anthropometric values (circumference at the waist and hip; resting heart rate and blood pressure)[Baseline and 16 weeks];Blood serum levels of brain derived neutrophic factor (BDNF).[Baseline and 16 weeks];Physical functioning as measured by the six-minute walk test, the timed up and go test and the one-leg stance test[Baseline and 16 weeks]