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临床试验/NCT00350935
NCT00350935已完成不适用

Attention and Grouping of Visual Information: What is Disturbed in Patients With Schizophrenia?

University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家目标入组 52 人开始时间: 2006年9月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
52
试验地点
1

研究概览

简要总结

The main objective of the study is to contribute to a better understanding of the physiopathology of schizophrenia, by studying causal relationships between cognitive deficits and the neurobiological basis for these deficits. Processing visual information involves both automatic grouping processes and control processes. Automatic grouping processes allow the building of a global configuration from local contour information. It is necessary in order to recognize objects. Control processes allow tending to and prioritizing information parts. The paradigm the investigators use allows to dissociate these processes, and is used in order to characterize the impairments observed in patients with schizophrenia. It is adapted to fMRI in order to explore the neurobiological basis of the deficits. The investigators will examine whether functional disconnectivity between activated areas subtend the impairments observed in patients.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with schizophrenia (DSM-IV criteria)
  • Healthy controls matched with patients on age, sex and education level
  • Ages 18 to 50
  • Signed informed consent
  • Right-handed

排除标准

  • No severe somatic illness
  • No invalidating sensory disease
  • No drug abuse, as defined by DSM-IV criteria
  • No general anaesthesia in the past 3 months
  • No intake of drugs affecting the CNS, except for patients

研究者

发起方
University Hospital, Strasbourg, France
申办方类型
Other

研究点 (1)

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