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临床试验/NCT00350935
NCT00350935
已完成
不适用

Attention and Grouping of Visual Information: What is Disturbed in Patients With Schizophrenia?

University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家目标入组 52 人2006年9月
适应症Schizophrenia

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Schizophrenia
发起方
University Hospital, Strasbourg, France
入组人数
52
试验地点
1
状态
已完成
最后更新
15年前

概览

简要总结

The main objective of the study is to contribute to a better understanding of the physiopathology of schizophrenia, by studying causal relationships between cognitive deficits and the neurobiological basis for these deficits. Processing visual information involves both automatic grouping processes and control processes. Automatic grouping processes allow the building of a global configuration from local contour information. It is necessary in order to recognize objects. Control processes allow tending to and prioritizing information parts. The paradigm the investigators use allows to dissociate these processes, and is used in order to characterize the impairments observed in patients with schizophrenia. It is adapted to fMRI in order to explore the neurobiological basis of the deficits. The investigators will examine whether functional disconnectivity between activated areas subtend the impairments observed in patients.

注册库
clinicaltrials.gov
开始日期
2006年9月
结束日期
2009年4月
最后更新
15年前
研究类型
Observational
性别
All

研究者

发起方
University Hospital, Strasbourg, France

入排标准

入选标准

  • Patients with schizophrenia (DSM-IV criteria)
  • Healthy controls matched with patients on age, sex and education level
  • Ages 18 to 50
  • Signed informed consent
  • Right-handed

排除标准

  • No severe somatic illness
  • No invalidating sensory disease
  • No drug abuse, as defined by DSM-IV criteria
  • No general anaesthesia in the past 3 months
  • No intake of drugs affecting the CNS, except for patients

结局指标

主要结局

未指定

研究点 (1)

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