Influence of Routine Use of Narrow Band Imaging on Heterotopic Gastric Mucosa of the Proximal Esophagus Detection
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Heterotopic Gastric Mucosa of the Proximal Esophagus
- Sponsor
- Tomasz Romańczyk
- Enrollment
- 1000
- Locations
- 1
- Primary Endpoint
- Detection of heterotopic gastric mucosa in the proximal esophagus
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The aim of the study is to determine whether Narrow Band Imaging(NBI) should be routinely used during esophagus inspection at diagnostic gastroscopy.
Detailed Description
Heterotopic gastric mucosa, also called inlet patch, is area of ectopic gastric mucosa with common location at proximal part of esophagus. Because of the location, lesions are likely to be missed during routine gastroscopy. The clinical significance of inlet patches remains unknown, however they may be symptomatic and may cause morphologic changes such as strictures, ulcers, webs, stenoses or even adenocarcinomas. Moreover inlet patches may be correlated with reflux symptoms up to 73,1%. Several studies were conducted to determine whether NBI improves detection of cervical inlet patches, some of them were also prospective studies, however no randomized study was conducted.
Investigators
Tomasz Romańczyk
Principal Investigator Tomasz Romańczyk MD, PhD
H-T. Centrum Medyczne Sp. z o.o. sp. k
Eligibility Criteria
Inclusion Criteria
- •Referral for diagnostic gastroscopy
- •Ability to undergo diagnostic gastroscopy
- •Provided written informed consent
Exclusion Criteria
- •Prisoners
- •Pregnancy
- •Gastroscopy with treatment procedure
- •Inability to provide informed consent
Outcomes
Primary Outcomes
Detection of heterotopic gastric mucosa in the proximal esophagus
Time Frame: Day 1
Secondary Outcomes
- Detection of other upper gastrointestinal lesions(Day 1)
- Correlation of throat and esophageal reflux symptoms with cervical inlet patches(Day 1)
- Total and esophagus inspection time(Day 1)
- Rate of cervical inlet patches verified with NBI in endoscopies performed in standard white light endoscopy(Day 1)
- Correlation of subject's subjective purpose of gastroscopy and cervical inlet patch occurrence(Day 1)