MedPath

Influence of Routine Use of Narrow Band Imaging on Heterotopic Gastric Mucosa of the Proximal Esophagus Detection

Not Applicable
Completed
Conditions
Heterotopic Gastric Mucosa of the Proximal Esophagus
Registration Number
NCT03015571
Lead Sponsor
Tomasz Romańczyk
Brief Summary

The aim of the study is to determine whether Narrow Band Imaging(NBI) should be routinely used during esophagus inspection at diagnostic gastroscopy.

Detailed Description

Heterotopic gastric mucosa, also called inlet patch, is area of ectopic gastric mucosa with common location at proximal part of esophagus. Because of the location, lesions are likely to be missed during routine gastroscopy. The clinical significance of inlet patches remains unknown, however they may be symptomatic and may cause morphologic changes such as strictures, ulcers, webs, stenoses or even adenocarcinomas. Moreover inlet patches may be correlated with reflux symptoms up to 73,1%. Several studies were conducted to determine whether NBI improves detection of cervical inlet patches, some of them were also prospective studies, however no randomized study was conducted.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1000
Inclusion Criteria
  • Referral for diagnostic gastroscopy
  • Ability to undergo diagnostic gastroscopy
  • Provided written informed consent
Exclusion Criteria
  • Age <18
  • Prisoners
  • Pregnancy
  • Gastroscopy with treatment procedure
  • Inability to provide informed consent

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Detection of heterotopic gastric mucosa in the proximal esophagusDay 1
Secondary Outcome Measures
NameTimeMethod
Detection of other upper gastrointestinal lesionsDay 1
Correlation of throat and esophageal reflux symptoms with cervical inlet patchesDay 1
Total and esophagus inspection timeDay 1
Rate of cervical inlet patches verified with NBI in endoscopies performed in standard white light endoscopyDay 1
Correlation of subject's subjective purpose of gastroscopy and cervical inlet patch occurrenceDay 1

Trial Locations

Locations (1)

H-T.Centrum Medyczne Sp. z o.o. Sp. K.

🇵🇱

Tychy, Silesia, Poland

H-T.Centrum Medyczne Sp. z o.o. Sp. K.
🇵🇱Tychy, Silesia, Poland

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.