Effect of Regular Physical Activity in Normal-Weight Individuals With Type 2 Diabetes and Abdominal Obesity
- Conditions
- Diabetes (DM)Physical Activity
- Registration Number
- NCT07071545
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
Individuals with T2DM accompanied by abdominal obesity tend to experience worse clinical outcomes. To identify modifiable factors that may improve these outcomes, the investigators conducted a retrospective cohort study using data from the Korean National Health Insurance Service (K-NHIS) database to evaluate the impact of regular physical activity.
- Detailed Description
It is well established that patients with T2DM and abdominal obesity have worse clinical outcomes. This holds true even among individuals with a normal body weight but central (abdominal) obesity. In this study, the investigators aimed to determine whether engaging in regular physical activity (defined as vigorous exercise at least three times per week) is associated with improved clinical outcomes in normal-weight individuals with abdominal obesity. Specifically, we compared the incidence of MACCE between normal-weight patients with type 2 diabetes who had abdominal obesity and those who did not.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 249247
- Patients who were newly diagnosed with T2DM and had a normal body weight at the time of diagnosis.
- Patients with any pre-existing diabetes-related complications
- Patients who were overweight or obese based on BMI criteria
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Major adverse cardiac and cerevrovascular events (MACCE) 10 years after diagnosed T2DM Composite of all-cause death, myocardial infarction, ischemic stroke, heart failure
- Secondary Outcome Measures
Name Time Method All cause death 10 years after diagnosed T2DM Death from all cause
myocardial infarction 10 years after diagnosed T2DM MI with hospitalization
Ischemic stroke 10 years after diagnosed T2DM Ischemic stroke after diagnosed T2DM
Heart failure 10 years after diagnosed T2DM HF with hospitalization
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