Effects of Citicoline in patients with traumatic concussio

Phase 1

• Conditions: head trauma.; Diffuse brain injury; S06.2

• Registration Number: IRCT20140611018063N7
• Lead Sponsor: Birjand University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 April 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Traumatic Head concussion
GCS lower or equal to 8
Hospitalized in ICU and Neurosurgery ward
Age between 5 to 60 years

Exclusion Criteria

severe cognitive disorders
severe systemic disorder
penetrating or open skull trauma
severe chest or lung trauma
subdural or large epidoral hematoma requiring surgery
younger than 5 or older than 60 years
pregnant women

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
evel of consciousness in a patients. Timepoint: First 7 days and on 14th day of hospitalization. Method of measurement: Glasgow Coma Scale scoring system.;Muscle strength degree. Timepoint: The first week, on day 14, 21 and 30 of hospitalization. Method of measurement: Manual Muscle Testing scale.;Contusion volume and cerebral edema. Timepoint: Days 1, 3, 5 and 7. Method of measurement: Computed Tomography scans.;Length of dependency on a ventilator. Timepoint: 30 days of hospitalization. Method of measurement: Documentary Registry Data.;Stay length in the intensive care unit. Timepoint: 30 days of hospitalization. Method of measurement: Documentary Registry Data.