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Clinical Trials/ACTRN12606000491561
ACTRN12606000491561
Completed
Phase 2

A pilot randomised controlled trial of home-based progressive resistant exercises and usual care compared to usual care alone for patients with venous leg ulcers

Principal investigator (Andrew Jull)0 sites40 target enrollmentNovember 28, 2006

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Venous leg ulceration
Sponsor
Principal investigator (Andrew Jull)
Enrollment
40
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The exercise programme consisted of three sets progressive repetitions (80% of the participant's maximum number, re-prescribed every three weeks) of two-legged heel raises every alternate day. All participants received compression with a system of their own or their nurse's choosing and any dressing could be used. The outcomes were change in calf muscle pump function, changes in ulcer area, number of participants with healed ulcers, time-to-complete healing, and adverse events. Participants were followed up for 12 weeks after randomisation. Forty participants were randomly assigned to an exercise programme or usual care (compression alone). Calf muscle pump changes favoured the exercise group, but the healing outcomes did not. The latter outcomes may have been influenced by an imbalance of large ulcers randomised to the exercise group. More adverse events were reported in the exercise group than the usual care group.

Registry
who.int
Start Date
November 28, 2006
End Date
September 21, 2007
Last Updated
5 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Principal investigator (Andrew Jull)

Eligibility Criteria

Inclusion Criteria

  • Community\-based diagnosis of venous ulceration based on case definition of clinical presentation, absence of other causative diseases and ankle\-brachial index greater than 0\.8; able to be treated with compression therapy; able to give informed consent; and able to perform at least one heel raise.mmunity\-based diagnosis of venous ulceration based on case definition of clinical presentation, absence of other causative diseases and ankle\-brachial index greater than 0\.8; able to be treated with compression therapy; able to give informed consent; and able to perform at least one heel raise.

Exclusion Criteria

  • History of rheumatoid arthritis; exercise intervention contraindicated by unstable medical condition such as heart failure.

Outcomes

Primary Outcomes

Not specified

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