Probing Neural Circuitry for the Control of Movement

University of Zurich1 site in 1 country250 target enrollmentMay 2004

ConditionsNeurological Movement Disorders

Overview

Phase: N/A
Intervention: Not specified
Conditions: Neurological Movement Disorders
Sponsor: University of Zurich
Enrollment: 250
Locations: 1
Primary Endpoint: Spinal reflex activity
Status: Completed
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The investigators are interested in examining 1) the basic organization of spinal and cortical circuitry for the control of movement and 2) the influence of injury of these circuits. To investigate the neuronal circuitry, the investigators use various types of mechanical or electrical stimulation of the limbs, transcranial magnetic stimulation of the cortex and galvanic vestibular stimulation in both uninjured human subjects and subjects with a neurological injury (such as spinal cord injury, or Parkinsons's disease).

Registry

clinicaltrials.gov

Start Date

May 2004

End Date

July 31, 2020

Last Updated

3 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

University of Zurich

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•control subjects: no neurological movement disorder
•patients: neurological movement disorder

Exclusion Criteria

•patients and control subjects:
•presence of any central psychiatric disorder that precludes subject from giving informed and voluntary consent
•presence of any cardiovascular conditions or limitations that restrict the ability to walk on a treadmill continuously for more than 20 minutes
•for the electrical stimulation examination, subjects with metal implants are also excluded
•for the TMS and GVS examination, subjects with the following conditions are excluded: metal implants in the head, cardiac pacemakers, history of migraine headaches, history of major head injury, history of stroke, history of seizures, previous brain neurosurgery, unstable medical conditions, major psychiatric disorders, pregnancy -