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Clinical Trials/NCT05338944
NCT05338944
Recruiting
Not Applicable

Dialectal Behaviour Therapy to Enhance Health Behaviour Change for Adolescents Living With Obesity (DIRECTION Trial)

University of Manitoba3 sites in 1 country90 target enrollmentJanuary 14, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Prevention
Sponsor
University of Manitoba
Enrollment
90
Locations
3
Primary Endpoint
Enrollment rates
Status
Recruiting
Last Updated
6 months ago

Overview

Brief Summary

This research is being conducted to evaluate emotion-focused therapy that incorporates elements of mindfulness, distress tolerance, and relationship support. The investigators want to learn if this therapy, called Dialectical Behavioral Therapy (DBT) will help improve quality of life and weight management in youth at risk for type 2 diabetes. Individuals will be randomly assigned to weekly group based session in one of 3 intervention arms; lifestyle + DBT, lifestyle alone, or a control arm.

Registry
clinicaltrials.gov
Start Date
January 14, 2023
End Date
January 31, 2027
Last Updated
6 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jon McGavock

Principal Investigator

University of Manitoba

Eligibility Criteria

Inclusion Criteria

  • 14-17 years old
  • BMI z-score \>1.4
  • signs of mild-moderate depression (PHQ-9 score 5-19)
  • willing and able to comply with study procedures

Exclusion Criteria

  • more than one health co-morbidity
  • being treated with medication for obesity
  • taking steroids
  • currently being treated for atypical antipsychotics
  • have an orthopedic injury or chronic illness that would prevent them from performing the intervention
  • experienced weight loss or enrolled in weight loss program in the six months prior to the study
  • they are currently and/or in the past 12 months have been prescribed any weight loss medication(s) including Ozempic
  • self reported history of alcoholism or drug abuse
  • history of self-harm or suicide attempts in the past 12 months
  • currently enrolled in psychotherapy or DBT

Outcomes

Primary Outcomes

Enrollment rates

Time Frame: 16 weeks

defined as the number of adolescents/families who consent to participate and are randomized to one of the arms of the study

Adherence to the intervention

Time Frame: 16 weeks

defined as the percentage of prescribed sessions that adolescents/families attend during the trial

Retention for follow up measurements

Time Frame: Measured at week 16 and week 32

defined as the number of adolescents who complete follow up measurements at 16 weeks and 32 weeks

Secondary Outcomes

  • Quality of Life measure using the PedsQL questionnaire(Measured at baseline, 16 weeks and 32 weeks)
  • Body Mass Index (BMI) z-score(Measured at baseline, 16 weeks and 32 weeks)
  • Body composition measured by dual-x-ray absorptiometry (DXA)(Measured at baseline, 16 weeks and 32 weeks)
  • Emotional regulation(Measured at baseline, 16 weeks and 32 weeks)
  • Emotional reactive eating(Measured at baseline, 16 weeks and 32 weeks)
  • Depressive symptoms(Measured at baseline, 16 weeks and 32 weeks)
  • Psychological distress(Measured at baseline, 16 weeks and 32 weeks)
  • Anxiety symptoms(Measured at baseline, 16 weeks and 32 weeks)
  • Readiness for Lifestyle Behavior Change(Measured at baseline, 16 weeks and 32 weeks)
  • Sleep habits(Measured at baseline, 16 weeks and 32 weeks)
  • Objective physical activity and sleep patterns(Measured at baseline, 16 weeks and 32 weeks)
  • Behavior regulation in exercise(Measured at baseline, 16 weeks and 32 weeks)
  • Self-reported healthy lifestyle behaviors - physical activity and screen time(Measured at baseline, 16 weeks and 32 weeks)

Study Sites (3)

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