ACTRN12610000428066已完成4 期
A randomised double blind, placebo controlled, cross-over study of the effect of amiloride over 6 weeks, on renal water handling in individuals with a bipolar or unipolar disorder, requiring lithium therapy
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 60 Years（—）
- 性别
- All
入选标准
- •Inclusion criteria.
- •All patients aged 18 to 60, with a bipolar or unipolar affective disorder requiring the commencement of lithium to manage their psychiatric disorder, and who are able to give informed consent.
排除标准
- •Exclusion criteria.
- •Any individual who is unable to give informed consent.
- •Any patients with evidence of renal impairment (plasma creatinine > 0.12 mmol/l)
- •Any patient unable to comply with a fluid restriction.
- •Any previous exposure to lithium
- •Pregnancy, thyroid disease.
- •Any contraindication to amiloride.
- •Thiazide or Angiotensin converting enzyme inhibitors, requirement for potassium supplements.
研究者
相似试验
已完成
2 期
The effects of butyrylated high amylose maize starch (Starplus B) on polyposis in familial adenomatous polyposis patientsFamilial Adenomatous PolyposisOral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colonACTRN12612000804886Royal Melbourne Hospital49
进行中（未招募）
1 期
A double blind, randomised, placebo controlled crossover study of intra-trigonal injections of Botulinum toxin type B for treating patients with idiopathic detrusor overactivity refractory to other conservative treatments. - Neurobloc crossoverIdiopathic detrusor overactivityEUCTR2005-004716-75-GBSwansea NHS Trust20
招募中
2 期
A double blind, placebo controlled, randomized crossover, pilot study of topical RM191A spray for the relief of neuropathic paiACTRN12617000206325RR MedSciences Pty Ltd22
招募中
1 期
Sleep disturbances in subjects with asthma and rhinitis”ACTRN12606000095561The Woolcock Institute30
已完成
不适用
Blackcurrant juice study: a study to investigate the biokinetics and effects of a blackcurrant juice on endothelial functioAbsorption of phytochemicals and effects on endothelial functionNutritional, Metabolic, EndocrineISRCTN26166772GlaxoSmithKline Nutritional Healthcare (UK)20