Phase II study of nedaplatin for advanced or relapsed squamous cell lung cancer in chemo-naive elderly patients
- Conditions
- squamous cell lung cancer
- Registration Number
- JPRN-UMIN000007054
- Lead Sponsor
- Shizuoka Cancer Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 25
Not provided
1) Patients with brain metastasis in need of steroid or anticonvulsant. 2) Less than 4 weeks after curative radiotherapy to primary lesion or less than 2 weeks after palliative radiotherapy. 3) History of active double cancer. 4) Patients with superior vena cava syndrome. 5) Uncontrollable pleural effusion, pericardial effusion or ascites. 6) History of uncontrollable hypertension, diabetes mellitus, active angina pectoris, active gastrointestinal hemorrhage, recent cardiac incompetence, recent myocardial infarction and active viral infection (except viral hepatitis). 7) Interstitial shadow of UIP (usual interstitial pneumonia) pattern on chest CT. 8) History of severe drug allergy. 9) History of severe psychiatric disease. 10) Patients whose participation in the trial is judged to be inappropriate by the attending doctor.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method response rate
- Secondary Outcome Measures
Name Time Method Overall survival, Progression free survival, Adverse events