NCT00079170已完成不适用
A Pilot Study to Evaluate the Influence of Garlic on the Pharmacokinetics of Docetaxel in Patients With Metastatic Breast Cancer
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 试验地点
- 2
研究概览
简要总结
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether garlic supplements affect the ability of docetaxel to kill tumor cells.
PURPOSE: This clinical trial is studying how well giving docetaxel together with garlic works in treating patients with locally advanced or metastatic breast cancer.
详细描述
OBJECTIVES:
Primary
- Determine the clinical pharmacokinetic behavior of docetaxel with and without garlic tablets in patients with locally advanced or metastatic breast cancer.
- Determine the toxicity of this regimen in these patients.
Secondary
- Determine the incidence of enzyme and transporter polymorphism in patients treated with this regimen.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究者
研究点 (2)
Loading locations...
相似试验
终止
2 期
Neoadjuvant Docetaxel in Treating Women With Newly Diagnosed Breast CancerBreast CancerNCT00080626Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins19
已完成
2 期
Two Regimens of Docetaxel in Treating Patients Who Have Not Received Chemotherapy For Unresectable Stage IIIB or Stage IV Non-Small Cell Lung CancerLung CancerNCT00075374Case Comprehensive Cancer Center6
已完成
2 期
Docetaxel in Treating Older Patients With Locally Advanced or Metastatic Non-Small Cell Lung CancerLung CancerNCT00227708UNICANCER58
终止
2 期
Docetaxel in Treating Older Women With Metastatic Breast CancerBreast CancerNCT00104624UNICANCER53
终止
2 期
S0224, Docetaxel in Treating Patients With Locally Advanced or Metastatic Penile Cancer (TERMINATED)Penile CancerNCT00058448SWOG Cancer Research Network1