Prospective Cohort Study of Sudden Sensorineural Hearing Loss in Wonju Severance Christian Hospital
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Hearing outcome 1 week - PTA
研究概览
简要总结
This study is to build a cohort of sudden sensorineural hearing loss (SSNHL) patients. When the patient visited the Department of otolaryngology clinic for hearing loss, we can diagnose the SSNHL following the result of pure tone audiometry and the history of the patient. The cohort is a system that tracks the hearing recovery status, timing, and degree of recovery of patients who received cocktail therapy with or without high-dose steroids, vasodilators, antiviral agents, and intratympanic steroid injections, satellite ganglion block, and hyperbaric oxygen therapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients over 20 years of age
- •A patient who visited Wonju Severance Christian Hospital, Department of Otolaryngology and was diagnosed with sudden hearing loss as it was confirmed that hearing loss of 30dBHL or more occurred within 3 days at three consecutive frequencies in a pure tone audiometry test.
- •Those who have fully explained the purpose and content of the study and voluntarily agreed to the written consent
排除标准
- •If the patients do not want to or do not fill out the consent form
- •If treatment is started for sudden hearing loss, but the possibility of other inner ear diseases including Meniere's disease is suspected due to repeated hearing loss, repeated recovery, dizziness, tinnitus, etc.
- •Other cases where it is judged difficult to carry out the clinical trial due to the judgment of the person in charge of the above clinical trial
结局指标
主要结局
Hearing outcome 1 week - PTA
时间窗: 1 week PTA
Hearing change status near 1 weak after treatment start measured by pure tone audiometry1
Hearing outcome 3 weeks - PTA
时间窗: 3 weeks PTA
Hearing change status near 3 weaks after treatment start measured by pure tone audiometry
Hearing outcome 3 months - PTA
时间窗: 3 month PTA
Hearing change status near 3 months after treatment start measured by pure tone audiometry
Hearing outcome 6 months - PTA
时间窗: 6 months PTA
Hearing change status near 6 months after treatment start measured by pure tone audiometry, which is final.
Hearing outcome 2 months - PTA
时间窗: 2 month PTA
Hearing change status near 3 weaks after treatment start measured by pure tone audiometry
次要结局
- Electrolytes and chemistries after high dose steroid therapy(5 days electrolytes and chemistries)
研究者
Tae Hoon Kong, MD, PhD
Assistant Professor
Wonju Severance Christian Hospital