A Single Group Evaluation of Concentrated Exposure and Response Prevention for Children With Obsessive-compulsive Disorder
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Childrens Yale-Brown Obsessive-Compulsive Scale (CY-BOCS)
研究概览
简要总结
The goal of this clinical trial is to evaluate the preliminary outcomes of concentrated exposure and response prevention for children with obsessive-compulsive disorder (OCD) in regular clinical practice. It is a non-randomised open label evaluation where children 6-12 years with OCD who are patients at the Child and Adolescent Psychiatry (CAP) at Uppsala University Hospital will be rectruited together with their legal guardians. The treatment will be delivered by trained therapists in regular outpatient care.
The main question the study aims to answer is:
What are the preliminary treatment effects of concentrated exposure and response prevention with regards to OCD-symptoms, functional impact, family accomodation and clinician ratings of severity and improvement?
Participants will receive psychoeducation (in group format) and exposure and response prevention (9-12h concentrated to one week, individual format).
Outcomes will be measured on structured interviews, clinician ratings, and validated questionnaires pre-treatment, post-treatment and at a six month follow-up.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patient fulfills the diagnostic criteria of obsessive-compulsive disorder
- •The patient and the legal guardians have said yes to receiving the concentrated exposure with response prevention - treatment
排除标准
- •The patient/legal guardians are unable to communicate in Swedish
结局指标
主要结局
Childrens Yale-Brown Obsessive-Compulsive Scale (CY-BOCS)
时间窗: pre-intervention; one week after the intervention; six months after the intervention
The Childrens Yale-Brown Obsessive-Compulsive Scale is a semi-structured interview made up of 10 items rated on a 5-point Likert scale evaluating the severity of Obsessions and Compulsions across five dimensions; Frequency, Interference, Distress, Resistance, and Control, during the previous week and up to the time of interview. The total score varies between 0 and 40. Higher scores indicate higher severity of Obsessions and Compulsions.
次要结局
- Clinical Global Impression (CGI)(pre-intervention; one week after the intervention; six months after the intervention)
- Dimensional Obsessive-Compulsive Scale - Child Version (DOCS-CV)(pre-intervention; one week after the intervention; six months after the intervention)
- The Obsessive Compulsive Inventory-Child Version (OCI-CV)(pre-intervention; one week after the intervention; six months after the intervention)
- Dimensional Obsessive-Compulsive Scale - Parent Version (DOCS-PV)(pre-intervention; one week after the intervention; six months after the intervention)
- The Family Accommodation Scale for Obsessive Compulsive Disorder - Self-Rated Version (FAS-SR)(pre-intervention; one week after the intervention; six months after the intervention)
研究者
Vendela Zetterqvist
Associate professor
Uppsala University Hospital