Incidence of Post-operative Cystoid Macular Edema: A Prospective Study Comparing DMEK, DSEK, and DSO
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 4
- 试验地点
- 1
- 主要终点
- Severity of Post-Op CME
研究概览
简要总结
This study aims to evaluate and compare incidence of post-operative cystoid macular edema (CME) after Descemet Membrane Endothelial Keratoplasty (DMEK), Descemet's Stripping Automated endothelial Keratoplasty (DSEK) and Descemet Stripping Only (DSO).
详细描述
Patients that are undergoing any of these procedures will be asked if they are willing to have a baseline pre-operative Optical Coherence Tomography (OCT) scan completed within 4 weeks of surgery. Additional OCT scans will be collected during routine follow up care. It is hypothesized that the rates of CME will be lower with DSO compared to DMEK and DSEK.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any patient that is undergoing DSO or endothelial corneal transplantation vis DMEK or DSEK
排除标准
- •Patients that do not have an optical coherence tomography measurement pre- operatively
- •Patients that don't have an optical coherence tomography measurement post- operatively
- •Patients with a previous history of uncontrolled macular edema
结局指标
主要结局
Severity of Post-Op CME
时间窗: 3 months post-operative
The severity of post-operative Cystoid Macular Edema will be evaluated for patients receiving DMEK, DSEK or DSO that experience Cystoid Macular Edema after surgery - measured by net change of Central Foveal Thickness on Optical Coherence Tomography (OCT- is an imaging technique that uses low-coherence light to capture micrometer-resolution, two- and three-dimensional images from within optical scattering media, e.g., biological tissue)
Incidence of Post-Op CME
时间窗: 3 months post-operative
The frequency (number of Subjects) of post-operative Cystoid Macular Edema will be evaluated for patients receiving DMEK, DSEK or DSO.
次要结局
- Graft Detachment(6 weeks and 3 months post-operative)
- Infection(6 weeks and 3 month post-operative)
- Re-bubbling Procedure(6 weeks and 3 months post-operative)
- Final Visual Acuity(3 months post-operative)