Observational Study on Seroprevalence of Hepatitis E Infection in Healthy Blood Donors in the Canton Ticino
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,447
- 试验地点
- 1
- 主要终点
- HEV blood incidence
研究概览
简要总结
This is a HEV seroprevalence in the health donors in the Canton Ticino study. The pre-donation sampling pouch of each blood donor coming form the Cantone Ticino region will be collected and tested for HEV serology (IgM and IgG).
详细描述
Pre-donation sampling pouch of fresh and stored frozen plasma collected within the last 5 years will be tested for HEV IgG serology at the National Reference Laboratory of the Blood Transfusion Services SRC in Berne Collected data will be used to determine HEV seroprevalence, actual and in the last 5 years, in the Canton Ticino and to investigate trend and pattern of the HEV infection (seroprevalence by different regional areas, comparison with national HEV data, and correlation with age, sex and place of residence).
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Healthy and voluntary blood donors
- •Subjects living in the Canton Ticino
- •Inclusion criteria for blood donation
- •Signed informed consent of the STCRS SI for blood donation
排除标准
- •Exclusion criteria for blood donation
结局指标
主要结局
HEV blood incidence
时间窗: One year
HEV incidence assessed through a single periferal blood sample from each donor
次要结局
- change in the blood incidence of HEV(Five years)
- Geogarphical distribution of the HEV measured in the blood sample(Five years)
- Trend of the HEV infection measured in the blood sample(One year)