Assessment of the Neurovascular Microcirculatory Response in Diabetes Type 1 Patients
Not Applicable
Completed
- Conditions
- Diabetes Mellitus Type 1
- Interventions
- Other: Microvascular assessment
- Registration Number
- NCT02538120
- Lead Sponsor
- University Hospital, Angers
- Brief Summary
This study aims to see whether or not the diabetes 1 patients have a neurovascular microcirculatory dysfunction using various microvascular tests which have been previously validated.
Microvascular responses will be assessed by Laser Speckle Contrast Imaging and expressed in Laser Speckle Perfusion Units (LSPU).
- Detailed Description
The investigators will compare microvascular responses between diabetes type 1 patients with matched control-subjects.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Diabetes type 1 patients
- Matched control-subjects
Exclusion Criteria
- Patients or subjects with anti-inflammatory drugs
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Diabetes type 1 patients Microvascular assessment The intervention will be : Microvascular assessment with laser speckle contrast imaging Matched control-subjects Microvascular assessment The intervention will be : Microvascular assessment with laser speckle contrast imaging
- Primary Outcome Measures
Name Time Method Neurovascular microcirculatory response one day Neurovascular response will be assessed by laser speckle contrast imaging using various microvascular tests such as deionized water iontophoresis, local heating test. Results will be explained in Laser Speckle Perfusion Units (LSPU)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital
🇫🇷Angers, France