The effect of IV antibiotics on gut flora during an episode of fever in children with cancer.
Recruiting
- Conditions
- Systemic antibiotics, microbiota, pediatric patients with cancer, febrile neutropenia.
- Registration Number
- NL-OMON21552
- Lead Sponsor
- niversity Medical Centre Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
Pediatric patients with cancer hospitalised in University Medical Centre Groningen
- Reason of hospitalization is febrile neutropenia
Exclusion Criteria
- No defecation within the first three days of hospitalization
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Number of specific bacterial groups in feces of pediatric patients
- Secondary Outcome Measures
Name Time Method - The difference in diversity of the microbiota before and after treatment<br /><br>- Type of systemic antibiotics<br /><br>- Laboratory values (Hb, CRP, leukocytes)<br /><br>- Blood cultures<br /><br>- Temperature<br /><br>- Type of nutrition