Investigation on bronchoalveolar lavage technique as an evaluation of drug migration to lung tissue - Investigation on bronchoalveolar lavage technique as an evaluation of drug migration to lung tissue

Medical Co. LTA Clinical Pharmacology Center0 sites6 target enrollmentJanuary 18, 2014

Overview

No summary available.

Registry

who.int

Start Date

January 18, 2014

End Date

February 5, 2014

Last Updated

2 years ago

Study Type

Interventional

Sex

Male

Sponsor

Medical Co. LTA Clinical Pharmacology Center

•1, Subject who has allergy or had hypersensitivity to lidocaine and/or azithromycin hydrate. And/or subject with illness which prohibits administration of these substances. 2, Subject with history of drug allergy. 3, Subject who received medical treatment 2 months prior to BAL. 4, Subject who donated more than 400ml or 200ml of blood within 3 months or 1 month prior to BAL, respectively. 5, Subject whose result of screening examinations (include vital sign, 12\-lead ECG, and safety laboratory tests) deviates from reference range, and the deviation is judged clinically significant by study physician. 6, Subject who takes drug habitually and/or who abuses alcoholic beverage. 7, Subject who acquired severe medical illness within 4 months prior to BAL. 8, Subject with positive test results of syphilis, HIV antigen/antibody, HBs antigen, and/or HCV antibody. Or subject with sign of infection. 9, Subject who smokes within 6 months prior to BAL. 10, Subject who are considered to be inadequate for this study by study physician.