Blinded Resection Avoided in Case of the Pancreatic Insulinoma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 197
- 主要终点
- No hidden insulinomas
研究概览
简要总结
The blinded resection avoided in case of pancreatic insulinoma
详细描述
Despite of the technique and technology developement there are still a lot of troubles to verify small benign-looking pancreatic NETs. It can be especially important in case of insulinoma. The organic hyperilsulinism and severe hypoglicemia causeb by the insulin/proinsulin - producing lesion can lead to severe complications and evem death.
There are some cases of the blinded resections of the pancreas in patients with the "hidden" insulinoma when the tumor can't be revealed during the preoperative diagnostics and intraoperatively. Unfortunately, blind resection do not solve the problem of the hypoglicemia but also cause the specific pancreatic complications.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Other
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The blinded resection of the insulinoma
排除标准
- •Other tumors
结局指标
主要结局
No hidden insulinomas
时间窗: 2010 June - 2020 June
To improve the diagnostics of the tumor before and during the surgery. The "hidden" insulinomas haven't been diagnosed. The frozen section have to be routinely performed. The surgery haven't been finished before the morphologic confirmation of the resected lesion.
次要结局
未报告次要终点
研究者
Ayrat Kaldarov
Dr. Ayrat Kaldarov
Vishnevsky Center of Surgery