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Self-Sampling for Human Papillomavirus (HPV) Testing in African American Women - Mississippi Delta

Not Applicable
Completed
Conditions
Cervical Cancer
Interventions
Behavioral: Choice
Behavioral: Pap testing
Registration Number
NCT03713710
Lead Sponsor
University of Alabama at Birmingham
Brief Summary

The purpose of this study is to examine the efficacy and costs of this patient-centered approach ("Choice" between two cervical cancer screening modalities) in adherence to cervical cancer screening as compared to the current standard of care within the public health system in Mississippi (Pap test at the local department -"Pap") among un/under-screened African American women in the Mississippi Delta using a theory-based, culturally relevant intervention implemented by Peer Health Educators (PHEs).

Detailed Description

OBJECTIVE: Our objective is to examine the efficacy and costs of a patient-centered approach ("Choice" between self-sampling and Pap test) in adherence to cervical cancer screening as compared to Pap test at the local health department ("Pap") among un/under-screened African American women in the Mississippi Delta.

HYPOTHESES: Women in the "Choice" arm will have a higher cervical cancer screening adherence as well as higher satisfaction than women assigned to the "Pap" arm; (2) Within the "Choice" arm, more women will choose and complete self-sampling than Pap test; and (3) The "Choice" intervention will be on average less costly and more cost-effective than the "Pap" intervention.

SPECIFIC AIMS: (1) To compare the impact of these two intervention approaches, "Choice" versus "Pap", on cervical cancer screening adherence through a group randomized controlled trial; (2) To compare patient satisfaction between the two intervention approaches; and (3) To compare the costs and cost-effectiveness of these two intervention approaches, "Choice" versus "Pap".

STUDY DESIGN: 12 towns will be randomized to either "Choice" or "Pap" (180 women/arm). Peer Health Educators (PHEs) will identify African American women who report not having undergone cervical cancer screening in the past three years and deliver a brief theory-based, cultural relevant educational session on cervical cancer and screening using a door-to-door approach. Women randomized to the "Pap" arm will be provided with information on how to schedule an appointment at the local health department. Women randomized to the "Choice" arm will be given the choice of attending the health department for a Pap test or self-collecting their own sample at home to be sent for HPV testing. PHEs will follow-up with women in either arm who have a positive test in order to assure diagnostic evaluation and care.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
335
Inclusion Criteria
  • no personal history of cervical cancer
  • not have engaged in cervical cancer screening in the past four years
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Exclusion Criteria
  • none
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ChoiceChoiceWomen assigned to this arm will be given a choice between scheduling an appointment for a Pap testing at the health department or engage in self-sampling for HPV testing at home
Pap testingPap testingWomen assigned to this arm will be scheduled a Pap testing appointment at the local health department
Primary Outcome Measures
NameTimeMethod
adherence to cervical cancer screeningbaseline to 30 days

adherence to cerivcal cancer screening by attending the Pap testing or returning the self-collected sample for HPV testing

Secondary Outcome Measures
NameTimeMethod
Satisfaction with the interventionbaseline to 6 months

We will assess participants' satisfaction with intervention through self-report (satisfaction questionnaire - satisfied/very satisfied)

Trial Locations

Locations (1)

Mississippi State Department of Health

🇺🇸

Jackson, Mississippi, United States

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