Pilot Study of a Multi-Pronged Intervention Using Social Norms and Priming to Improve Adherence to Antiretroviral Therapy and Retention in Care Among Adults Living With HIV in Tanzania
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- HIV Infection
- Sponsor
- University of California, Berkeley
- Enrollment
- 438
- Locations
- 2
- Primary Endpoint
- Retention in care, defined as an attended visit between 150-210 days after the baseline visit
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
Interventions incorporating constructs from behavioral economics and psychology have the potential to enhance HIV 'treatment as prevention' (TasP) strategies. To test this hypothesis, the investigators evaluated a combination intervention to improve antiretroviral therapy (ART) adherence based on the concepts of social norms and priming.
Detailed Description
The investigators conducted a quasi-experimental pilot study of a combination behavioral intervention based on the concepts of social norms and priming. The intervention included visual feedback about clinic-level retention in care, a self-relevant prime, and useful take-home items with the priming image. The intervention was developed using tools from marketing research and patient-centered design. The hypothesis was that the intervention would improve retention in care and adherence to ART among patients living with HIV infection (PLHIV). The intervention was implemented at two HIV primary clinics in Shinyanga, Tanzania in 2-week intervals for six months. The investigators reviewed medical records of a random sample of exposed and unexposed adult PLHIV to compare retention and the proportion of patients with medication possession ratio (MPR) ≥95% after six months.
Investigators
Eligibility Criteria
Inclusion Criteria
- •At least 18 years of age
- •Living with HIV infection
- •Receiving HIV primary care at one of the two study clinics
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Retention in care, defined as an attended visit between 150-210 days after the baseline visit
Time Frame: 6 months
This measure of retention in care accounts for variability in visit scheduling by individual providers and therefore uses a window period of 150-210 days to determine whether the patient was in care at 6 months
>=95% medication possession ratio (MPR)
Time Frame: 6 months
MPR is a measure of ART adherence that is correlated with viral suppression
Secondary Outcomes
- The proportion of scheduled visits that were completed during the 6-month observation period(6 months)
- Medication possession ratio (MPR), continuous scale(6 months)