Role of Red Cell Distribution Width to Platelet ratio which can be obtained from a Blood test (CBC) to differentiate the severe cases of Acute Pancreatitis from mild cases in the early phase of the attack to provide aggressive treatment to severe cases from the initial time.

Recruiting

• Conditions: Acute pancreatitis, unspecified, (2) ICD-10 Condition: K860||Alcohol-induced chronic pancreatitis, (3) ICD-10 Condition: K851||Biliary acute pancreatitis, (4) ICD-10 Condition: K853||Drug induced acute pancreatitis, (5) ICD-10 Condition: K850||Idiopathic acute pancreatitis,

• Registration Number: CTRI/2023/03/050564
• Lead Sponsor: Kasturba Medical College, Manipal

Brief Summary

Diagnosed cases of Acute Pancreatitis being admitted  in Department of General Surgery and Department of Gastroenterology , Kasturba Hospital, Manipal will be recruited in this study. Red cell distribution width to platelet ratio from Complete Blood Count will be calculated during the early phase of disease and will be compared with BISAP and APACHE II scoring in knowing the prognosis of acute pancreatitis in early phases.

Patients will be followed up till the time the time of discharge or death. The values obtained will be analysed and using various statistical tests following which conclusion will be made if CBC can be used for determining the prognosis of acute pancreatitis. Since CBC is a routine investigation and RPR ( Red cell distribution width to platelet ratio) is easy to calculate , this study will provide us with a marker from routine investigation to know the prognosis.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-03-22
• Last Update Posted: 2023-03-28

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• 1. case of Acute Pancreatitis presented to Kasturba Hospital, Maniapl.
• 2. patients who are 18 years and above.

Exclusion Criteria

• 1. Patient with pre existing pancreatitis (k/c/o chronic pancreatitis and pancreatic cancers) 2) Already included patient presented with recurrent attack will not be included again.
• 3. Patient has undergone any kind of surgery of pancreas.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Study will help to find a way to distinguish between severe cases of acute pancreatitis from milder cases in early phases Acute Pancreatitis and to proceed with the management accordingly.	From the time of Admission till Discharge or death time
Patients will be divided on the basis of severity: based on (REVISED ATLANTA CLASSIFICATION)	From the time of Admission till Discharge or death time
• In the two group of patients, commonly used scores will be used to measure the severity of acute pancreatitis at the time of admission	From the time of Admission till Discharge or death time
2) BISAP	From the time of Admission till Discharge or death time
• Scores that will be used for comparison are:	From the time of Admission till Discharge or death time
1) APACHE 11	From the time of Admission till Discharge or death time

Secondary Outcome Measures

Name	Time	Method
Study will help to find a way to distinguish between severe cases of acute pancreatitis from milder cases in early phases Acute Pancreatitis and to proceed with the management accordingly.	From the time of Admission till Discharge or death time

Trial Locations

Locations (1)

Kasturba hospital, Maniapl; 🇮🇳 Udupi, KARNATAKA, India

Kasturba hospital, Maniapl

🇮🇳Udupi, KARNATAKA, India

Dr Veena L Karanth

Principal investigator

9845417715

veena.karanth@manipal.edu