Comparison of outcomes in patients undergoing majorplanned surgeries before vs. after the implementation ofPatient Blood Management (PBM): a retrospective study infour European countries

• Conditions: D50; D62; D64; Iron deficiency anaemia; Acute posthaemorrhagic anaemia; Other anaemias

• Registration Number: DRKS00025903
• Lead Sponsor: Vifor International AG

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-12
• Study Completion: 2022-03-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 6460

Inclusion Criteria

?Adult patients = 18 years old at the time of hospital admission, and
? Adult patients that have gone under major elective surgery (hip arthropathy; knee arthropathy; major abdominal surgeries as colorectal or gastrointestinal cancer surgeries, and ovarian/uterine cancer surgeries; and cardiac valves), and
? Patients that have gone under major elective surgery during the corresponding time period depending on the cohort (pre- or post-PBM program implementation). Time periods are defined at site level depending on date of PBM program implementation.

Exclusion Criteria

Patients meeting ANY of the following criteria will not be eligible for participation:
- Patients <18 years old, or
- Patients with other pathologies that based on clinical criteria can impact on the implementation of PBM program and expected outcomes.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the transfusion outcomes of patients undergoing major planned surgeries before vs. after the implementation of PBM, after adjusting for potential confounders.

Secondary Outcome Measures

Name	Time	Method
- To compare other clinical outcomes of patients undergoing major planned surgeries before vs. after the implementation of PBM, after adjusting for potential confounders.<br>- To compare the economic outcomes of patients undergoing major planned surgeries before vs. after the implementation of PBM, after adjusting for potential confounders.<br>- To compare newly diagnosed health problems in patients undergoing major planned surgeries before vs. after the implementation of PBM, after adjusting for potential confounders