Treatment of skin severity in Ichthyosis with hyperbaric oxygen therapy
- Conditions
- Ichtyosis, bacterial skin infection, fungal skin infection
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 6
Inclusion Criteria
Confirmed diagnosis of ichtyosis, >18 years old, can understand Dutch or English language
Exclusion Criteria
Unfit for hyperbaric oxygen therapy (as determined by hyperbaric physician), unable to give informed consent, language barrier, actively smoking or stopped smoking <3 months ago
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Feasability of the intervention in this patient group; changes in PROMs (Patients Global Assessment, pain, desquamation, sleep and pruritus scores, medication usage and Quality of life using skindex-29); changes in doctors reported outcomes (objective skin scoring with IGA-NS, TLSS NS and BSA); assessing the safety and feasibility of HBO in patients with ichthyosis
- Secondary Outcome Measures
Name Time Method Changes in laboratory findings; Changes in histologic findings in skin biopsies reviewed by a pathologist; Side effects; Regret analysis