The Effect of peptide-based formula compared with standard polymeric formula by early enteral feeding in critically-ill patients

Thai Otsuka Pharmaceutical Co., Ltd0 个研究点目标入组 144 人开始时间: 2022年2月21日最近更新: 2024年8月19日

研究概览

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•1 Willing to attend the study with completed inform consent form ,2 Age 18 years old or above at date of consent ,3 Admits on Medical ICU ward ,4 On mechanical ventilator for 2 days or above ,5 Use enteral feeding via NG tube in ICU ward not less than 5 days and up to 14 days ,6 Has risk of malnutrition (5 points or more by Modified Nutric Score evaluation ) ,7 BMI 18-30 kg per m2 , 8 Could be prescribed enteral feeding within 48 hours after ICU admission ,9 Has hemodynamically stable. In case of patient need to take norepinephrine, the dose is not more than 15 microgram per minute or 0.3 microgram per kg per minute

•1 Does not have legal representative,2 Experiences aspiration pneumonia,3 Experiences thyroid disease ,4 Experiences severe hepatic impairment ,5 Experiences renal replacement therapy ,6 Diagnosed to abdominal hypertension ,7 Takes fentanyl more than 2 microgram per kg per hr or morphine more than 0.05 milligram per kg per hr, 8 Has parenteral nutrition administration,9 Experiences food allergy such as Whey Protein, Casein ,10 Diagnosed to incurable disease that could not participate the study such as uncontrolled cancer,11 Experiences chemotherapy or radiotherapy within 6 months ago. (including immunosuppressor taking such as prednisolone 7 days continuously within 4 months before enrolment ,12 Experiences immune disorder such as HIV-positive

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