Comparison of Lumbar Muscle Thickness Measurements in Osteoporotic and Osteopenic Patients

Completed

• Conditions: Osteoporosis
• Interventions: Diagnostic Test: Lomber Muscle Thickness Measurement

• Registration Number: NCT05823558
• Lead Sponsor: Sisli Hamidiye Etfal Training and Research Hospital

Brief Summary

In osteoporosis, sarcopenia is a common condition. Sarcopenic measurements can be made by evaluating muscle thickness in different regions. We aim to evaluate lumbar muscle losses in patients with osteoporosis in the lumbar region and to examine whether these muscle losses are correlated with the level of osteoporosis. The patients will be divided into 3 groups as healthy, osteopenic and osteoporotic according to DEXA measurements. Demographic values, comorbidities, osteoporosis drugs used, fracture histories, L1-4, L2-4, femoral neck and total BMD and t values of the patients, psoas and multifidus muscle measurements will be made at L2-L3 level in Lumbar MR imaging. Lumbar MR muscle measurements will be made by 1 physician blind to the DEXA values of the patients.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-04-10
• Study First Submitted QC: 2023-04-10
• Study First Posted: 2023-04-21
• Study Start: 2023-08-15
• Primary Completion: 2024-08-15
• Study Completion: 2024-08-30
• Status Verified: 2024-11
• Last Update Submitted: 2024-11-01
• Last Update Posted: 2024-11-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 301

Inclusion Criteria

• 50-90 years old
• 2. Recent MRI of the lumbar region with DEXA evaluation

Exclusion Criteria

• Have had previous lumbar surgery
• Any previous lumbar injection
• Stage 3-4 Lumbar Listesis
• Presence of Lumbar Discopathy accompanied by neurological deficit

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Osteopenic Patients Group	Lomber Muscle Thickness Measurement	T value between -2.5 and -1 in DEXA measurement
Healthy Group	Lomber Muscle Thickness Measurement	T value of -1 and above in DEXA measurement
Ostoporotic Patients Group	Lomber Muscle Thickness Measurement	T value of -2.5 and below in DEXA measurement

Primary Outcome Measures

Name	Time	Method
Lomber Muscle Measurement	Day 1	Psoas and multifidus muscle measurements will be made at L2-L3 level in Lumbar MR imaging.

Trial Locations

Locations (1)

Etfal Training and Research Hospital; 🇹🇷 Istanbul, Turkey