A clinical trial of nebulized surfactant for the Treatment of moderate to severe COVID-19 in adults - COVID-19 Surfactant Clinical Trial

niversity Hospital Southampton NHS Foundation Trust0 个研究点目标入组 20 人开始时间: 2020年5月11日最近更新: 2020年5月25日

适应症

试验速览

暂无简介。

•1.Age =18 years old
•2.Confirmed COVID-19 positive by PCR
•3.Within 24 hours of mechanical ventilation
•4.Assent obtained from personnel (PerLR) or professional legal representative (ProfLR)
•Are the trial subjects under 18? no
•Number of subjects for this age range: 0
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 10
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 10

•1.Imminent expected death within 24 hours
•2.Specific contraindications to surfactant administration (e.g. known allergy, pneumothorax, pulmonary haemorrhage)
•3.Known or suspected pregnancy
•4.Stage 4 severe chronic kidney disease or requiring dialysis (i.e., eGFR < 30)
•5.Liver failure (Child-Pugh Class C)
•6.Anticipated transfer to another hospital, which is not a study site within 72 hours.
•7.Current participation or participation in another study within the last month that in the opinion of the investigator would prevent enrollment for safety purposes.
•8.Consent declined

发起方

niversity Hospital Southampton NHS Foundation Trust